@article{Pankiv_Pashkovska_Pankiv_Maslyanko_Tsaryk_2021, title={Pathophysiological and clinical aspects of interaction between coronavirus disease 2019 and thyroid}, volume={17}, url={https://iej.zaslavsky.com.ua/index.php/journal/article/view/1080}, DOI={10.22141/2224-0721.17.4.2021.237348}, abstractNote={<p>In patients who were not previously diagnosed with any thyroid conditions, the scenario of COVID-19 related anomalies of the thyroid may include either: a process of central thyroid-stimulating hormone disturbances via virus‑related hypophysitis; an atypical type of subacute thyroiditis which is connected to the virus spread or to excessive cytokine production including a destructive process with irreversible damage to the gland or low triiodothyronine syndrome (non-thyroidal illness syndrome) which is not specifically related to the COVID‑19 infection, but which is associated with a very severe illness status. This review aimed to investigate thyroid changes resulted from the COVID-19 infection. Ongoing assessment of the effects of the COVID-19 pandemic will reveal more information on coronavirus-induced thyroid conditions. Routine thyroid assays performed in patients with severe infection/acute phase of COVID-19 are encouraged to detect thyrotoxicosis. After recovery, thyroid function should be assessed to identify potential hypothyroidism. There remain unanswered questions related to the predictive value of interleukin-6 in infected patients, especially in cases of cytokine storm, and the necessity of thyroid hormone replacement in subjects with hypophysitis-related central hypothyroidism.</p>}, number={4}, journal={INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine)}, author={Pankiv, V.I. and Pashkovska, N.V. and Pankiv, I.V. and Maslyanko, V.A. and Tsaryk, I.O.}, year={2021}, month={Jun.}, pages={329–333} }