Pathogenesis of diabetic retinopathy: a literature review
DOI:
https://doi.org/10.22141/2224-0721.15.7.2019.186061Keywords:
diabetic retinopathy, pathogenesis, reviewAbstract
The review presents data on the pathogenesis of diabetic retinopathy. The importance of increasing the activity of the polyol pathway of glucose metabolism, non-enzymatic glycation of proteins, activation of protein kinase C, carbonic anhydrase, hemodynamic changes and the activity of the renin-angiotensin system in the development of diabetes and its microvascular complications is indicated. Particular attention is paid to the role of oxidative stress, growth factors, as well as metabolic syndrome and obesity in the development and progression of diabetic retinopathy.Downloads
References
International Diabetes Association. IDF Diabetes Atlas. 7th ed. 2017. Available from: http://www.diabetesatlas.org/.
Kyryliuk ML, Serdiuk VM, Pylypenko LYu. Influence of the factors of the progression of diabetics rethinopathy on the concentration of blood fibrinogen at type 2 diabetes as the component of metabolic syndrome. Clinical Endocrinology and Endocrine Surgery. 2017;4(60):64-69. doi.org/10.24026/1818-1384.4(60).2017.118769
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Copyright (c) 2019 M.L. Kyryliuk, V.A. Іshchenko
This work is licensed under a Creative Commons Attribution 4.0 International License.