Biomarkers of iodine deficiency, methods of its prevention and treatment
Keywords:iodine deficiency, biomarkers, prevention, treatment
The review article focuses on the issue of iodine deficiency, which is very common in the world and leads to a significant number of health problems, including mental, intellectual, thyroid, and non-thyroid in all age groups. Today, in most countries, the introduction of iodine prevention has resulted in more than 60 % of the population overcoming iodine deficiency disorders, but the only category of the population even in these countries that still has such a deficit is pregnant and breastfeeding women. At this time, Ukraine has failed programs to provide the population with sufficient iodine, national research on this problem has not been conducted for several decades, so since 2021, on the maps of iodine status, Ukraine is already listed as a “white spot”. Therefore, iodine prevention is becoming a problem for the population of our country, every resident who wants to be healthy and have healthy offspring, must do it yourself. The best way to overcome iodine deficiency pathology is the daily use of a combination of iodine, selenium in WHO recommended and vitamin D in individual doses, constantly throughout the year with periodic laboratory monitoring of TSH (a marker of thyroid function, including screening), thyroglobulin as an individual marker iodine deficiency, and vitamin D, a marker of wealth, which determines the state of the musculoskeletal and parathyroid systems. Several studies have shown that the use of excessive doses of iodine can increase the development of thyroid pathology, but not all of them have a perfect design that takes into account other factors of such pathology. Today in Ukraine, there is a drug that contains a combination of iodine (150 mcg) and selenium (75 mcg) for adults. This safe ratio in the recommended doses for people aged over 12 years is the most optimal for the prevention and treatment of iodine deficiency pathology and conditions, is well established, popular among physicians and patients. Its simultaneous and long-term use with vitamin D preparations in individual doses over the years with periodic monitoring of laboratory parameters and ultrasound examination of the thyroid gland allows achieving in most cases these medical goals and objectives.
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