Diabetes Mellitus Induced by Exogenous Administration of Glucocorticoids

L.A. Nykytiuk


The questions of the diagnosis and treatment of steroid-induced diabetes mellitus are considered in the lecture.


diabetes mellitus; glucocorticoids


Trigolosova IV. Steroid induced diabetes mellitus. RMJ. 2016;1:54-56 (Russian)

Fardet L, Peterson I, Nazareth I. Prevalence of long-term oral glucocorticoid prescriptions in the UK over the past 20 years. Rheumatology. 2011;50(11):1982-1990.

Gulliford MC, Charlton J, Latinovic R. Risk of diabetes associated with prescribed glucocorticoids in a large population. Diabetes Care. 2006;29:2728–2729.

Papang R, John AS, Abraham S, Rao PS. A study of steroid-induced diabetes mellitus in leprosy. Indian J Lepr. 2009;81:125-129.

Donihi AC, Raval D, Saul M. еt al. Prevalence and predictors of corticosteroid-related hyperglycemia in hospitalized patients. Endocr Pract. 2006;12:358-362.

White BD, Dean RG, Edwards GL. et al. Type II corticosteroid receptor stimulation increases NPY gene expression in basomedial hypothalamus of rats. Am. J. Physiol. 1994;266(5 Pt 2):1523-9.

Raalte DH van, Nofrate V, Bunck MC. et al. Acute and 2-week exposure to prednisolone impair different aspects of beta-cell function in healthy men. Eur J Endocrinol. 2010;162:729-735.

Hansen KB, Vilsbøll T, Bagger JI. et al. Reduced glucose tolerance and insulin resistance induced by steroid treatment, relative physical inactivity, and high-calorie diet impairs the incretin effect in healthy subjects. Journal of Clinical Endocrinology and Metabolism. 2010;95(7):3309-3317.

Canadian Diabetes Association 2013 clinical practice guidelines for the prevention and management of diabetes in Canada. Can J Diabetes. 2013;37(1):1–212.

Management of Hyperglycaemia and Steroid (Glucocorticoid) Therapy. JBDS. October 2014.

Zheng D, Ionut V, Mooradian V. et. al. Exenatide sensitizes insulin-mediated whole-body glucose disposal and promotes uptake of exogenous glucose by the liver. Diabetes. 2009;58:352–359.

Van Raalte DH, Van Genugten RE, Linssen MM. et al. Glucagon-like peptide-1 receptor agonist treatment prevents glucocorticoid-induced glucose intolerance and islet-cell dysfunction in humans. Diabetes Care. 2011;34:412-417.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.


© "Publishing House "Zaslavsky", 1997-2019


   Seo анализ сайта