Influence of Overweight and Obesity on Reproductive Health and Carrying of a Pregnancy

О.О. Коrytko

Abstract


The lecture considers the influence of obesity in women of reproductive age on somatic and reproductive problems that results in the decline of fertility. Women with obesity in comparison to the women with normal body weight have an increase in both frequency of spontaneous pregnancies and efficiency of treatment for sterility using different methods (stimulation of ovulation and other). After the occurrence of pregnancy in women with obesity, there is an increase in the risks of congenital abnormalities, macrosomia, stillbirth, gestational hypertension, gestational diabetes, premature birth and a number of other complications. Weight loss has a positive effect on menstrual function, increases the probability of conception and birth of a healthy child, reduces the risk of adverse pregnancy outcomes.


Keywords


obesity; reproductive function; pregnancy; review

References


American College of Obstetricians and Gynecologists. ACOG Committee opinion no. 549: obesity in pregnancy. Obstet Gynecol. 2013;121:213.

Owens LA, O’Sullivan EP, Kirwan B. et al. ATLANTIC DIP: the impact of obesity on pregnancy outcome in glucose-tolerant women. Diabetes Care. 2010;33:577.

Ramsay JE, Ferrell WR, Crawford L. et al. Maternal obesity is associated with dysregulation of metabolic, vascular, and inflammatory pathways. J Clin Endocrinol Metab. 2002;87:4231.

Marshall NE, Guild C, Cheng YW. et al. Maternal superobesity and perinatal outcomes. Am J Obstet Gynecol. 2012;206:417.

Reynolds RM, Allan KM, Raja EA. et al. Maternal obesity during pregnancy and premature mortality from cardiovascular event in adult offspring: follow-up of 1 323 275 person years. BMJ. 2013;347:4539.

Flegal KM, Carroll MD, Kit BK, Ogden CL. Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010. JAMA. 2012;307:491.

Ogden CL, Carroll MD, Kit BK, Flegal KM. Prevalence of obesity among adults: United States, 2011-2012. NCHS Data Brief. 2013;1:8.

Thatcher SS, Jackson EM. Pregnancy outcome in infertile patients with polycystic ovary syndrome who were treated with metformin. Fertil Steril. 2006;85:1002.

van der Steeg JW, Steures P, Eijkemans MJ. et al. Obesity affects spontaneous pregnancy chances in subfertile, ovulatory women. Hum Reprod. 2008;23:24.

Kort JD, Winget C, Kim SH, Lathi RB. A retrospective cohort study to evaluate the impact of meaningful weight loss on fertility outcomes in an overweight population with infertility. Fertil Steril. 2014;101:1400.

Souter I, Baltagi LM, Kuleta D. et al. Women, weight, and fertility: the effect of body mass index on the outcome of superovulation/intrauterine insemination cycles. Fertil Steril. 2011;95:1042.

Hugues JN. Impact of overweight on the outcome of ovarian stimulation. Bull Acad Natl Med. 2008;192(4):661-670.

Rittenberg V, Seshadri S, Sunkara SK. et al. Effect of body mass index on IVF treatment outcome: an updated systematic review and meta-analysis. Reprod Biomed Online. 2011;23:421.

Jungheim ES, Schon SB, Schulte MB. et al. IVF outcomes in obese donor oocyte recipients: a systematic review and meta-analysis. Hum Reprod. 2013;28:2720.




DOI: https://doi.org/10.22141/2224-0721.7.79.2016.86415

Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

 

© "Publishing House "Zaslavsky", 1997-2017

 

 Яндекс.МетрикаSeo анализ сайта Рейтинг@Mail.ru