Comparative Analysis of Violations of Physical and Sexual Development in Children and Adolescents (Boys) with Various Mass Lesions of the Hypothalamic-Pituitary Region

Yu.M. Urmanova, U.Kh. Mavlonov

Abstract


In this paper, the authors analyze the results of the survey 29 adolescent boys with different mass lesions of the hypothalamic-pituitary region. It is established a variety of disorders of growth and development, such as growth retardation (20.6 %), delayed growth and puberty (20.6 %), true precocious puberty (13.8 %), etc. The most commonly encountered patients with inactive pituitary adenoma — 11 cases out of 29 (37.9 %). The most frequently delayed physical and sexual development was observed in patients with inactive pituitary adenoma — in 6 cases (20.6 %).


Keywords


tumors of the hypothalamic-pituitary region; impaired physical and sexual development; adolescents; boys; risk factors

References


Кириченко К.Н. Диагностика и хирургическое лечение кранио-

фарингиом у детей. Нейроэндокринные нарушения в до- и послеоперационном периодах: Дис... канд. мед. наук. — СПб., 2005. — 128 с.

Кондратьев А.Н. Антиноцицептивная защита при хирургических операциях на головном мозге: Методические рекомендации. — Л., 1989. — 8 с.

Мельников Б.Ф. Опухоли головного мозга у детей раннего возраста / Б.Ф. Мельников: Автореф. дис... канд. мед. наук. — Киев, 1976.

Мазеркина Н.А. Соматотропная функция гипофиза и периферические ростовые факторы у детей с краниофарингиомой: Автореф. дис... канд. мед. наук. — М., 1996.

Мазеркина Н.А. Эндокринные нарушения после комплексной терапии злокачественных опухолей хиазмально-селлярной области и задней черепной ямки у детей: Дис... д.м.н. — М., 2008. — 183 с.

Савин И.А. Осложненное течение раннего послеоперационного периода при краниофарингиомах у детей / И.А. Саввин: Автореф. дис... канд. мед. наук. — М., 1996.

Ценципер Л.М. Основные типы течения послеоперационного периода и принципы терапии у детей с опухолями гипоталамо-гипофизарной локализации: Дис… канд. мед. наук. — СПб., 2004. — 146 с.

Banna M. Craniopharyngioma in children / M. Banna, R.D. Hoare, P. Stanley // J. Pediatr. — 1973. — Vol. 83. — P. 781.

Copinschi G. et al. Enhanced ACTH and blunted cortisol responses to corticotropin-releasing factor in idiopathic panhypopituitarism // J. Pedi. — 1984. — 105. — 591.

Dashe A.M. et al. A water deprivation test for the differential diagnosis of polyuria // JAMA. — 1963. — 185. — 699.

Dunkel L. et al. Gonadotropin-releasing hormone test and human chorionic gonadotropin test in the diagnosis of gonadotropin deficiency in prepubertal boys // J. Pediatr. — 1985. — 107. — 388.

Duff J.M., Meyer F.B., Ilstup D.M. et al. Long-term outcomes for surgicaly resected craniopharingiomas // J. Neurosurg. — 2000. — Vol. 46, № 2. — P. 291.

Ehrmann D.A. et al. A new test of combined-testicular function using gonadotropin-releasing hormone agonist Nafarelin in the differentiation gonadotropin deficiency from delayed puberty: Pilot studies // J. Clin. Endocrinol. Metab. — 1989. — 69. — 963.

Frasier S.D. Pediatric Endocrinology. — New York: Grune and Stratton, 1980.

Frasier S.D. et al. A water deprivation test for the diagnosis of Diabetes insipidus in children // Am. J. Dis. Child. — 1967. — 114. — 157.

Kaplan S.A. (ed.). Clinical Pediatric and Adolescent Endocrinology. — Philadelphia: Saunders, 1982.

Knoers N., Monnens L. Amiloride-hydrochlorothiazide vs. indomethicine hydrochlorothiazide in the treatment of nephrogenic diabetes insipidus // Pediatr. — 1990. — 117. — 499.

Lyer K.R. Endocrine function, morbidity and mortality after surgery for craniopharyngioma // Archiver of diseause of childhood. — 1982. — Vol. 57. — P. 837-841.

Mendoza S.A. Syndrome of inappropriate antidiuretic hormone secretion // S. Pediatr. Clin. North Am. — 1976. — 23. — 681.

Partsch C.-J. et al. Differentiation of male hypogonadotropic hypogonadism constitutional delay of puberty by pulsatile administration of gonadotropin releasing hormone // J. Clin. Endocrinol. Metab. — 1985. — 60. — 1196.

Robertson G.L. Differential diagnosis of polyuria // Annu Rev. Med. — 1985. — 39. — 425.

Stosel H., Braunstein G. Endocrine abnormalities associated with Langerhans cell histiocytosis // The Endocrinologist. — 1991. — 1. — 393.

Tien R.D. et al. Thickened pituitary stalk on MR image in patients with and DI. // AJNR. — 1990. — 11. — 703.

Williams R.D. Textbook of Endocrinology. — 7th ed. — Philadelphia: Saunders, 1985.

Yanovski J. et al. Repeated, childhood vaginal bleeding is not always precocious puberty // Pediatrics. — 1992. — 89. — 149.




DOI: https://doi.org/10.22141/2224-0721.6.54.2013.84632

Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

 

© "Publishing House "Zaslavsky", 1997-2017

 

 Яндекс.МетрикаSeo анализ сайта Рейтинг@Mail.ru