Nelson’s Syndrome: Questions and Answers (Clinical Case)

Main Article Content

Z.P. Nizhinska-Astapenko
M.V. Vlasenko
N.I. Hurina

Abstract

This clinical case reflects the variability in the course of chronic adrenal insufficiency after bilateral adrenalectomy for Itsenko — Cushing disease, the development and growth of pituitary adenoma, which can lead to hemorrhagic stroke in the most recurrent pituitary tumor. The objective of pathogenetic treatment is to reduce the secretion of adrenocorticotropic hormone secretion, to restore normal secretion of tropic pituitary hormones, as well as the prevention of further growth of pituitary tumor and adequate compensation of adrenal insufficiency. The case shows labile course of postoperative adrenal insufficiency and, consequently, different approaches to the diagnosis and the need for substitution therapy at different stages of the disease.

Article Details

How to Cite
Nizhinska-Astapenko, Z., M. Vlasenko, and N. Hurina. “Nelson’s Syndrome: Questions and Answers (Clinical Case)”. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine), no. 4.76, Aug. 2016, pp. 127-30, doi:10.22141/2224-0721.4.76.2016.77825.
Section
Clinical Case

References

Даневич О.О. Вплив гіпофізарної апоплексії на клінічний перебіг та результати лікування хвороби Кушинга / О.О. Даневич, М.О. Гук, Д.С. Тесленко // Проблеми ендокринної патології. — 2014. — № 3. — ​С. 67-71.

Панькив В.И. Синдром Нельсона / В.И. Панькив // Международный эндокринологический журнал. — 2013. — № 6(54). — ​С. 43-47.

Рожинская Л.Я. Клиническая нейроэндокринология / под ред. И.И. Дедова. — ​М.: УП Принт, 2011. — ​С. 79-93.

Болезнь Иценко — ​Кушинга / под ред. И.И. Дедова, Г.А. Мельниченко. — ​М., 2011. — 344 с.

Боднар П.Н. Эндокринология. — ​Винница: Новая книга, 2007. — 344 с.

Марова Е.И. Синдром Нельсона: рук-во по клинической эндокринологии / под ред. Н.Т. Старковой. — ​СПб.: Питер, 1996. — ​С. 78-83.

Most read articles by the same author(s)

1 2 > >>