Structural Changes of Thyroid Gland in Victims of Chernobyl Disaster with Type 2 Diabetes Mellitus

Main Article Content

I.M. Muravyova
I.G. Chykalova

Abstract

According to the objective of the study, we have carried out a research of clinical relationships between diabetes mellitus (DM) type 2 and nonmalignant thyroid disease in victims of Chernobyl disaster in remote post-accident period (148 persons) and in control group (38 persons). We have obtained data on the nature and incidence of thyroid organic pathology. The incidence of thyroid organic pathology in patients with DM type 2, who are victims of Chernobyl disaster (58.3 ± 6.3 %), is statistically significant (p < 0.05) higher than in control group (43.1 ± 3.9 %). Dominating pathology in patients with type 2 DM, who are victims of Chernobyl disaster, is nodular euthyroid goiter, the incidence of which (26.7 ± 5.7 %) in 3.3 time higher (p < 0.01) than in control group (8.1 ± 2.2 %), and depends on sex, age and duration of underlying disease.

Article Details

How to Cite
Muravyova, I., and I. Chykalova. “Structural Changes of Thyroid Gland in Victims of Chernobyl Disaster With Type 2 Diabetes Mellitus”. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine), no. 4.60, July 2014, pp. 21-25, doi:10.22141/2224-0721.4.60.2014.76678.
Section
Original Researches

References

Паньків В.І. Взаємозв’язок між патологією щитоподібної залози і цукровим діабетом 2 типу / В.І. Паньків // Здоров’я України. — 2013. — № 2 (22). — С. 36-37.

Крутиков Е.С. Структурно-функциональные нарушения щитовидной железы у больных сахарным диабетом 2-го типа / Е.С. Крутиков, В.А. Цветков, А.С. Глушко // Таврический медико-биологический вестник. — 2013. — Т. 16, № 3. — С. 71-74.

Крутиков Е.С. Влияние сниженной функции щитовидной железы на течение и развитие сосудистых осложнений сахарного диабета 2-го типа / Е.С. Крутиков, В.А. Цветков, А.С. Глушко // Міжнародний ендокринологічний журнал. — 2014. — № 2 (58). — С. 93-96.

Brenta G. A view of diabetes from the thyroid corner / G. Brenta // Thyroid International. — 2013. — № 3. — P. 1-20.

Duntas L.H. The Interface between thyroid and diabetes mellitus / L.H. Duntas, J. Orgiazzi, G. Brabant // Clin. Endocrinol. (Oxf.). — 2011. — № 75. — Р. 1-9.

Crunkhorn S. Links between thyroid hormone action, oxidative metabolism, and diabetes risk? / S. Crunkhorn, M.E. Patti // Thyroid. — 2008. — № 18 (2). — Р. 227-237.

Kadiyala R. Thyroid dysfunction in patients with diabetes: clinical implications and screening strategies / R. Kadiyala, R. Peter, O.E. Okosieme // Int. J. Clin. Pract. — 2010. — № 64 (8). — Р. 1130-1139.

Yang J.K. An association between subclinical hypothyroidism and sight-threatening diabetic retinopathy in type 2 diabetic patients / J.K. Yang, W. Liu, J. Shi, Y.B. Li // Diabetes Care. — 2010. — № 33 (5). — Р. 1018-1020.

Most read articles by the same author(s)