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The aim of the work was to determine the characteristics of intracardiac hemodynamics in patients with essential hypertension (EH) stage II in combination with type 2 diabetes mellitus (DM). The research involved 120 patients aged 53.7 ± 5.6 years and 30 apparently healthy individuals of the same age. The main group consisted of 60 patients with essential hypertension stage II with the second (30 patients) and the third (30 patients) degree of arterial hypertension (AH). The comparison group included 30 patients with type 2 diabetes mellitus and 30 patients with EH stage II.
The intracardiac hemodynamics was studied with the help of the digital Doppler ultrasound diagnostic scanner Ultima Pro-30 with the examination of systolic and diastolic function of the left ventricle (LV) according to generally accepted criteria.
It was found that comparison group (patients with type 2 DM), as compared with group of healthy individuals, showed a significant changes of indicators which determine the left ventricular systolic function — increase of the linear and volumetric parameters of LV against decrease of its contractile function. In the comparison group (patients with EH stage II) the specified parameters changed in the same direction and were more reliable in comparison with the patients with type 2 DM. In the main group the mentioned changes of indicators characterizing the left ventricular systolic function were more expressed and significantly differed from the control group of the patients with EH. The most significant were also parameters that characterized the left ventricular diastolic function in the patients of the main group (EH associated with type 2 DM) and they mostly depended on the level of LV hypertrophy. It should also be noted that changes in the indicators of systolic and diastolic LV function directly depended on blood pressure level and were significantly and maximally changed in the third degree of AH hypertension.
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