Studying the Impact of Combined Application of Iodine and Selenium on the Course of Most Common Thyroid Pathology

I.A. Kiseliova, A.V. Kaminskyi

Abstract


In this paper we examine the presence of micronutrient deficiencies in Ukraine, influencing the efficacy of the thyroid gland functions and the development of thyroid pathology. A clinical experience of using a fixed combination of trace elements iodine and selenium in physiological doses for preventing such violations is described. The possibility of the impact of this combination on the stabilization of thyroid pathology and safety of application in autoimmune diseases is proved.


Keywords


thyroid gland; micronutrient deficiency; iodine; selenium; diffuse nontoxic goiter; nodular goiter; Hashimoto’s thyroiditis

References


WHO. Assessment of the Iodine Deficiency Disorders and monitoring their elimination: a guide for programme managers, 3rd ed. [Text] / WHO. — Geneva, 2007. — P. 1-98.

UNICEF Ukraine. AWP: Micronutrient malnutrition Project: Elimination of Iodine Deficiency: Request for Applications // UNICEF Ukraine. — 2009. — Р. 22. — Доступ: http://www.unicef.org/ukraine.doc.

ICCIDD: The Iodine Global Network. — 2015. — Доступ: http://www.ign.org.

Дзахмишева И.Ш. Профилактика йододефицита функциональными продуктами питания // Фундаментальные исследования. — 2013. — № 10. — С. 2418-2421. — Доступ: http://rae.ru/fs/pdf/2013/10-11/32806.pdf/

Факти для життя. Довідковий посібник. Розроблено спільно Представництвами Дитячого фонду ЮНІСЕФ в Україні, Білорусії та Російській Федерації. Київ — Мінськ — Москва, березень 2008 р. — 192 с. — Доступ: http://www.unicef.org/ukraine/ukr/6_FFL_Chernobyl_Edition.pdf/

Karanikas G. No immunological benefit of selenium in consecutive patients with autoimmune thyroiditis / G. Karanikas, M. Schuetz, S. Kontur et al. // Thyroid. — 2008. — № 18. — Р. 7-12.

Pizzulli A. Selenium deficiency and hypothyroidism. A new etiology in the differential diagnosis of hypothyroidism in children [Text] / A. Pizzulli, A. Ranjbar // Biological Trace Element Research. — 2000. — Vol. 77, № 3. — P. 199-208.

Emerson C.H. A Personalized Medicine Month in Minneapolis, Minnesota [Text] / C.H. Emerson // Thyroid. — 2010. — V. 20, № 4. — P. 355-356.

Hercberg S. The SU.VI.MAX Study: a randomized, placebo-controlled trial of the health effects of antioxidant vitamins and mineral / S. Hercberg, P. Galan, P. Preziosi et al. // Arch. Intern. Med. — 2004. — Vol. 164, № 21. — Р. 2335-2342.

Duntas L.H. Environmental factors and autoimmune thyroiditis / L.H. Duntas // Nature Clinical Practice Endocrinology and Metabolism. — 2008. — № 4. — Р. 454-460.

Toulis K.A. Selenium supplementation in the treatment of Hashimoto’s thyroiditis: a systematic review and a meta-analysis / K.A. Toulis, A.D. Anastasilakis, T.G. Tzellos et al. // Thyroid. — 2010. — № 20. — Р. 1163-1173.

Turker O. Selenium treatment in autoimmune thyroiditis: 9-month follow-up with variable doses / O. Turker, K. Kumanlioglu, I. Karapolat et al. // Journal of Endocrinology. — 2006. — 190. — Р. 151-156.

Gärtner R. Selenium in the treatment of autoimmune thyroiditis / R. Gärtner, B.C.H. Gasnier // BioFactors. — 2003. — № 19. — Р. 165-170.

Mazokopakis E.E. Effects of 12 months treatment with L-selenomethionine on serum anti-TPO Levels in Patients with Hashimoto’s thyroiditis / E.E. Mazokopakis, J.A. Papadakis, M.G. Papadomanolaki et al. // Thyroid. — 2007. — № 17. — Р. 609-612.

Nacamulli D. Influence of physiological dietary selenium supplementation on the natural course of autoimmune thyroiditis / D. Nacamulli, C. Mian, D. Petricca et al. // Clinical Endocrinology. — 2010. — Vol. 73. — Р. 535-539.

WHO/ICCIDD/UNICEF. Indicators for Assessing Iodine Deficiency Disorders and Their Control Through Salt Iodization. — Geneva, Switzerland: World Health Organization; 1994.

Thyroglobulin іs a Sensitive Measure of Both Deficient and Excess Iodine Intakes in Children and Indicates No Adverse Effects on Thyroid Function in the UIC Range of 100–299 μg/L: A UNICEF/ICCIDD Study Group Report / M.B. Zimmermann, I. Aeberli, M. Andersson et al. // J. Clin. Endocrinol. Metab. — 2013. — № 98(3). — Р. 1271-80.




DOI: https://doi.org/10.22141/2224-0721.2.66.2015.75451

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