Features of Thyroid Functional State in Patients with Type 2 Diabetes Mellitus and Obesity
We have observed 55 patients with diabetes mellitus (DM) type 2 and obesity without signs of thyroid function abnormality, as well as 60 patients with DM type 2 and obesity combined with overt or subclinical hypothyroidism. The objective of the study was to evaluate the indicators of thyroid functional state in patients with type 2 DM and obesity. It is shown that patients with type 2 DM combined with hypothyroidism have a higher incidence of hypertriglyceridemia. In these patients, there are higher rates of body weight, low-density lipoproteins (LDL) than in patients with type 2 DM without thyroid dysfunction. Patients with type 2 DM in combination with symptomatic hypothyroidism are characterized by higher levels of body weight, total cholesterol, LDL, triglycerides and lower high-density lipoproteins indicators than those with DM type 2 associated with subclinical thyroid dysfunction. With an increasing number of metabolic syndrome components, deterioration in carbohydrate and lipid metabolism is being detected in examined patients that can lead to increased cardiovascular risks.
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