Endogenous Peptide Apelin and Pathological Cardiac Remodeling in Hypertensive Patients with Diabetes Mellitus Type 2

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S.M. Koval
K.O. Yushko
T.H. Starchenko


The study involved 63 patients with essential hypertension and diabetes mellitus type 2. The control group consisted of 16 apparently healthy individuals. Complex of examination included conventional clinical-laboratory and instrumental methods, ultrasound of the heart with Doppler sonography, determining apelin blood concentration by ELISA. Patients with essential hypertension and diabetes mellitus type 2 compared with the control group had a probable reduction in apelin level associated with the development of pathological cardiac remodeling, increasing the size of the left atrium and diastolic dysfunction of the heart.

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How to Cite
Koval, S., K. Yushko, and T. Starchenko. “Endogenous Peptide Apelin and Pathological Cardiac Remodeling in Hypertensive Patients With Diabetes Mellitus Type 2”. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine), no. 5.69, Nov. 2015, pp. 37-40, doi:10.22141/2224-0721.5.69.2015.75077.
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