Anaplerosis in Complex Treatment of Patients with Diabetic Foot Syndrome

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B.G. Bezrodny
O.A. Radomskyi
M.O. Prystupiuk


The article describes the improvement of anaplerosis in patients with diabetic foot syndrome using skin flaps on vascular pedicle of the perforating vessels. The study involved patients with type 2 diabetes mellitus complicated with diabetic foot syndrome of neuroischemic form and chronic wounds of the lower extremities that do not heal for more than 21 days from the date of occurrence. The wounds were cleaned with ultrasonic cavitation. There was applied bandage with sorption antibacterial remedy base on nanodispersed silicon dioxide. There was applied a drainage vacuum bandage on a wound on the third day (VAC therapy). The flap is forming fitting to the size and configuration of a wound on a foot. Fourteen patients (93 %) in the basic group were found to have survived flaps. Long-term follow up in 6 months demonstrated full maintenance of supporting function and good survived skin graft, absence of foot ulcers. In a control group 7 patients had recurrent foot ulcer. Improved techniques of autodermoplasty in patients with diabetic foot syndrome include glycemia control, preparation of a wound using vacuum apparatus bandage. Usage of split-skin graft combined with vacuum apparatus bandage allows close acute and chronic wounds effectively, maintain supporting function of an extremity, decrease in-hospital staying, and improve quality of patient’s life. Adequate foot wound closure prevents high-level amputation of low extremities in diabetic patients.

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Bezrodny, B., O. Radomskyi, and M. Prystupiuk. “Anaplerosis in Complex Treatment of Patients With Diabetic Foot Syndrome”. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine), no. 4.68, July 2015, pp. 106-9, doi:10.22141/2224-0721.4.68.2015.75026.
Endocrine Surgery


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