Prevalence of Carbohydrate Metabolism Disorders in Urban Population of Ukraine Depending on the Degree and Type of Obesity

O.I. Mitchenko, M.N. Mamedov, T.V. Kolesnyk, A.D. Deiev, V.Yu. Romanov, O.Yu. Kulyk, A.O. Shkrioba

Abstract


The objective of this study was subanalysis of the prevalence and detection of carbohydrate metabolism disorders in patients with overweight and obesity depending on the degree and type of obesity in a large population study of risk factors carried out in Ukraine on urban population in 2009–2013. It is found that in analyzed urban population of Ukraine, only 29.3 % of subjects had normal body weight, and 70.7 % had total overweight and obesity of I–III degree. There was a trend to increasing prevalence of overweight and obesity with age in both men and women being examined. It is revealed that with increasing body weight and age, detection rate for carbohydrate metabolism disorders in the population increases. The total prevalence of all carbohydrate metabolism disorders in the population was 77.2 %. The percentage of carbohydrate metabolism disorders detection increased with increasing degree of obesity and age. With increasing body weight, insulin resistance (IR) detection rate increased from 16.8 % at normal body weight to 77.2 % at obesity of II–III degree, impaired glucose tolerance (IGT) — from 23.4 % at normal body weight to 36.9 % at obesity of II–III degree and detection rate for diabetes mellitus (DM) — from 3.4 to 16.3 %, respectively. The onset of abdominal obesity in men is associated with worsening of carbohydrate metabolism disorders and growth of IR detection rate by 35.4 %, IGT — by 5.6 %, DM — by 8.3 %. In women, the onset of abdominal obesity is associated with increased IR detection by 7.8 % and IGT — by 5.0 %, compared with women without signs of abdominal obesity.


Keywords


diabetes mellitus; impaired glucose tolerance; prevalence; overweight; obesity

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DOI: https://doi.org/10.22141/2224-0721.4.68.2015.74999

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