The Importance of Clinical and Diagnostic Markers of Aggression of Non-Functional Pituitary Adenomas

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Yu.M. Urmanova
Z.Yu. Khalimova
R.B. Faizullaev
M.Yu. Shakirova
D.Sh. Kholova

Abstract

Sixty patients with non-functional pituitary adenomas were observed. Most patients had large-cell chromophobe pituitary adenomas (81.6%). Small-cell chromophobe adenomas occurred in 10 % cases. Only 1 patient (3.3 %) had giant carcinoma with regrowth and metastasis into the brain. Markers of aggression of non-functional pituitary adenomas are the young age of a patient, expressed first symptoms of disease manifestation, large size of tumor, asymmetry and deformation of pituitary, invasion of tumor to the neighboring tissues/arteries/cavernous sinus, presence of small cell and dark-cell chromophobe adenoma, panhypopituitarism.

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How to Cite
Urmanova, Y., Z. Khalimova, R. Faizullaev, M. Shakirova, and D. Kholova. “The Importance of Clinical and Diagnostic Markers of Aggression of Non-Functional Pituitary Adenomas”. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine), no. 6.70, Nov. 2015, pp. 24-27, doi:10.22141/2224-0721.6.70.2015.72634.
Section
Original Researches

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