Lifestyle Changes in as a Prevention of Diabetes Mellitus

N.N. Zherdeva, R.P. Klymenko, O.L. Fruscheva


Insulin resistance is not only the cause of carbohydrate intolerance and diabetes mellitus type 2, but also the factor of the development of cardiovascular diseases. However, we are faced with the fact that patients are not always ready to take the drugs, even for the purpose of reducing the risk of such disease, as diabetes mellitus. Therefore, this group of patients should be offered alternative approaches to treatment.
The objective of our study was to determine the effect of Guarem on the carbohydrate, lipid metabolism and body weight in patients with impaired carbohydrate tolerance.
The study involved 60 patients with carbohydrate intolerance. Patients were divided into 3 groups of 20 people each.
The first group included patients who received statins as a lipid-lowering therapy, the second one — statins + fibrates, the third one — those who were not taking antidiabetic therapy. As a result of treatment, all groups showed a decrease in body weight: the 1st one — by 3.94 %, the second one — by 3.63 % and the third one — by 5.48 %. The significant reduction in total cholesterol and triglyceride levels after the treatment was observed in the group of those who were not taking lipid-lowering therapy. In the group of patients who received statins, a statistically significant decrease in triglyceride levels was observed. Thus, we can conclude that the use of Guarem, by slowing down the evacuation of the stomach, leads to weight loss, normalization of triglycerides, cholesterol levels, contributes to changes in dietary habits (adapts to the regimen of small, frequent feeding, reduction in the volume and caloric content of food).


impaired carbohydrate tolerance; obesity; grelin; guar gum; Guarem


Bonora E., Kiechl S., Willeit J. et al. Prevalence of insulin resistance in metabolic disorders: the Bruneck Study // Diabetes. — 1998. — 47(10). — 1643-1649.

Batnik M. et al. // Eur. Heart J. — 2004. — 26. — 1880-90.

UK Prospective Diabetes Study Group: Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33) // Lancet. — 1998. — 352. — 837-853.

DCCT: The Study That Forever Changed the Nature of Treatment of Type 1 Diabetes // British Journal of Diabetes and Vascular Disease. — 2004. — 4(1).

Standards of medical care in diabetes — 2015 // Diabetes care. — Jan 2015. — Vol. 38, Suppl. 1. — S. 31-32.

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