Phosphorus and Calcium Metabolism in Postmenopausal Women with Diabetes Mellitus: Effects of the Type and Duration of the Disease, Time of Menopause and Body Mass
The article deals with the impact of diabetes mellitus (DM) on the phosphorus and calcium metabolism in postmenopausal women, depending on the type and duration of the disease, duration of menopause, body mass and type of hypoglycemic therapy. The state of phosphorus and calcium metabolism in 86 women with type 1 DM (13 patients) and type 2 DM (73 patients) was studied. In all patients, the concentration of calcium and phosphorus in the blood was within normal limits. It was found that the concentration of ionized calcium, total calcium and inorganic phosphorus in the blood can not be the main criterion for the state of bone mineral density in postmenopausal women with DM. Sulfonylureas and insulin in combination with biguanides have no effect on the status of phosphorus and calcium metabolism in postmenopausal women with type 2 DM.
Sambrook P, Cooper C. Age-specific and sex-specific incidence of radiographic vertebral, hip and distal forearm fractures. Lancet. 2006; 367: 2010-8.
Van Staa TP, Dennison EM, Leufkens HE, Cooper C. Epidemiology of fractures in England and Wales. Bone. 2001; 29: 517-22.
Povoroznjuk VV, Dzerovich NI, Karasevskaya TA. Bone mineral density in Ukrainian women of different age. Annals of the New York Academy of Sciences. 2007;1119; 243-52.
Fucumoto S. Updates on lifestyle-related diseases and bone metabolism. Clin. Calcium. 2014; 24(11): 1701-5. doi: CliCa141117011705.
Adil C, Aydin T, Taşpınar Ö et al. Bone mineral density evaluation of patients with type 2 diabetes mellitus. J. Phys. Ther. Sci. 2015; 27(1):179-82. doi: 10.1589/jpts.27.179. Epub 2015 Jan 9.
Leidig-Bruckner G, Grobholz S, Bruckner T et al. Prevalence and determinants of osteoporosis in patients with type 1 and type 2 diabetes mellitus. BMC Endocr. Disord. 2014; Apr 11: 14-33. doi: 10.1186/1472-6823-14-33.
Ogata M, Ide R, Takizawa M, et al. Association between basal metabolic function and bone metabolism in postmenopausal women with type 2 diabetes. Nutrition. 2015; 31(11-12): 1394-401. doi: 10.1016/j.nut.2015.06.012.
.Kurra S, Siris E. Diabetes and bone health: the relationship between diabetes and osteoporosis-associated fractures. Diabetes Metab. Res. Rev. 2011.; 27(5): 430-5. doi: 10.1002/dmrr.1197.
МcNair P, Christiansen MS, Madsbad S et al. Hypoparathyroidism in diabetes mellitus. Acta Endocrinol. 1991; 96: 81-6.
Yamamoto M, Yamaguchi T, Nawata K, et al. Decreased PTH levels accompanied by low bone formation are associated with vertebral fractures in postmenopausal women with type 2 diabetes. Clin. Endocrinol. Metab. 2012; 97(4): 1277-84. doi: 10.1210/jc.2011-2537. Epub 2012 Feb 15.
- There are currently no refbacks.
This work is licensed under a Creative Commons Attribution 4.0 International License.
© "Publishing House "Zaslavsky", 1997-2017