Subclinical Hypercorticism: the Necessity of Diagnostic Search
Considering certain difficulties in subclinical hypercorticism diagnosis, the object of this work is to focus attention of doctors in different areas on the necessity of thorough examination of patients with pathological conditions that may be the manifestation of Cushing’s syndrome (arterial hypertension, obesity, impaired carbohydrate metabolism and osteoporosis). The laboratory diagnosis is the instrument for early subclinical hypercorticism detection.
Melmed S. Williams textbook of endocrinology. – 12th ed./S.Melmed [et al]. Philadelphia, 2012. 1920 р.
Findling JW, Raff H. Screening and diagnosis of Cushing’s syndrome. Endocrinol. Metab. Clin. North Am. 2005.;34:385-402.
Nieman L. Cushing’s syndrome: update on signs, symptoms and biochemical screening. Eur. J. Endocrinol. 2015; 173:33-38, doi: 10.1530/EJE-15-0464.
Chanson P, Salenave S. Metabolic syndrome in Cushing’s syndrome. Neuroendocrinology. 2010; 92(suppl 1): 96-101.
Anderson G, Blakeman N, Streeten DH.. The effect of age on prevalence of secondary forms of hypertension in 4,429 consecutively referred patients. J. Hypertens. 1994;12: 609-615.
Omura M. Prospective study on the prevalence of secondary hypertension among hypertensive patients visiting a general outpatient clinic in Japan. Hypertens. Res. 2004; 27: 193-202.
Faggiano A. Cardiovascular risk factors and common carotid artery caliber and stiffness in patients with Cushing’s disease during active disease and 1 year after disease remission. J. Clin. Endocrinol. Metab. 2003; 88: 2527-2533.
Fallo F. Effect of surgical treatment on hypertension in Cushing’s syndrome. Am. J.Hypertens. 1996; 9: 77-80.
Giordano R. Metabolic and cardiovascular outcomes in patients with Cushing’s syndrome of different etiologies during active disease and 1 year after remission. Clin. Endocrinol. (Oxf). 2011; 75: 354-360.
Catargi B. Occult Cushing’s syndrome in type-2 diabetes. J. Clin. Endocrinol. Metab. 2003; 88: 5808-5813.
Reimondo G. Screening of Cushing’s syndrome in adult patients with newly diagnosed diabetes mellitus. Clin Endocrinol (Oxf). 2007; 67: 225-229.
Chiodini I. Association of subclinical hypercortisolism with type 2 diabetes mellitus: a case-control study in hospitalized patients. Eur. J. Endocrinol. 2005; 153: 837-844.
Praveen EP. Morning cortisol is lower in obese individuals with normal glucose tolerance. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 2011; 4: 347-352.
Basu R. Obesity and Type 2 Diabetes Do Not Alter Splanchnic Cortisol Production in Humans. J. Clin. Endocrinol. Metab. 2005; 90: 3919-3926.
Ness-Abramof R. Overnight dexamethasone suppression test: a reliable screen for Cushing’s syndrome in the obese. Obes. Res. 2002; 10: 1217-1221.
Tiryakioglu O. Screening for Cushing’s syndrome in obese patients. Clinics (Sao Paulo). 2010; 65: 9-13.
Otdalennyie rezultatyi hirurgicheskogo lecheniya sindroma Kushinga, obuslovlennogo kortikosteromoy // Materialyi 9-go (11-go) Ros.simpoziuma po hirurgicheskoy endokrinologii [«Sovremennyie aspektyi hirurgicheskoy endokrinologii»] – Chelyabinsk, 2000. – S. 180 – 185.
Chiodini I. Subclinical hypercortisolism among outpatients referred for osteoporosis. Ann. Intern. Med. 2007; 147: 541-548.
Zografos GN, Perysinakis I, Vassilatou E. Subclinical Cushing's syndrome: current concepts and trends. Hormones (Athens). 2014;13 (3): 323-337.
Gatta B. Reevaluation of the combined dexamethasone suppression-corticotropin-releasing hormone test for differentiation of mild Cushing’s disease from pseudoCushing’s syndrome. J. Clin. Endocrinol. Metab. 2007; 92(11): 4290-4293.
Nieman LK. The Diagnosis of Cushing's syndrome: аn endocrine society clinical practice guideline. J. Clin. Endocrinol. Metab. 2008; 93: 1526-1540.
Terzolo M, Pia A, Reimondo G. Subclinical Cushing’s syndrome: definition and management. Clinical Endocrinology. 2012; 76:12-18.
Zeiger MA. American association of clinical endocrinologists and American association of endocrine surgeons medical guidelines for the management of adrenal incidentaloma. Endocrine practice. 2009;15: 1-20.
Ob'emnyie obrazovaniya nadpochechnikov (diagnostika i differentsialnaya diagnostika): metodicheskie rekomendatsii dlya vrachey, okazyivayuschih spetsializirovannuyu meditsinskuyu pomosch / E. A. Troshina [i dr.]. Pod red. I. I. Dedova, G. A. Melnichenko // Consilium Medicum. 2009; 11, # 12. – S. 76-94.
- There are currently no refbacks.
This work is licensed under a Creative Commons Attribution 4.0 International License.
© "Publishing House "Zaslavsky", 1997-2018