Prognostic Characteristics of Hypothyroidism Prevalence in the Poltava Region and in Ukraine under Conditions of Iodine Deficiency
Introduction. The increasing interest in the problem of thyroid pathology in recent years is determined by its growing prevalence among the population of Ukraine, and hypothyroidism is one of the most common pathology of the endocrine system. Objective — to conduct an analysis of the incidence and prevalence of hypothyroidism in Ukraine and Poltava region in conditions of iodine deficiency.
Materials and methods. Comparative analysis of thyroid pathology in Ukraine and in the Poltava region for the past 30 years has been carried out, the prevalence of hypothyroidism in 2005–2013 has been studied with the construction of predictive model of hypothyroidism prevalence in the Poltava region and in Ukraine in general.
Results. Poltava region belongs to the areas of moderate iodine deficiency. Since 1980, there was not only increased number of thyroid disease in general, but also the changes in its structure, specific weight of hypothyroidism in the Poltava region increased by 4.9 times, while in Ukraine — by 5.3. Analyzing the predictive models of hypothyroidism prevalence in the Poltava region, we state that with a probability of 95.6 %, from 2013 to 2019 this pathology can increase twofold and will range (interval forecast) from 5,220 to 5,853.
Conclusion. These data suggest that the constant growth of this pathology in various regions of Ukraine, in particular in the Poltava region, leads to the need to identify the features of development, clinical course, regimens of treatment and prevention depending on regional characteristics.
The report «On national study of the use population food micronutrients» // Kyyiv: «Prem"yer Media», 2004. — 64 s.
Pearce E.N. The global situation with the provision of iodine in 2013 / E.N. Pearce, M. Andersson, M.B. Zimmermann // Zdorov"ya Ukrayiny. Tematychnyy nomer «Endokrynolohiya». – cherven' 2013 r. — S. 34–35.
Zelinskaja N.B. Iodine deficiency disorders in Ukraine: modern state of the problem and possible solutions / N.B. Zelinskaja, M.E. Mamenko // Zdorov'e Ukrainy. – 2007. – № 1. – S. 37.
De Benua B. Elimination of iodine deficiency — one of the key objectives of health / B. De Benua, O.V. Shvec // Mezhdunarodnyj jendokrinologicheskij zhurnal. – 2011. – № 6. – S. 38-39.
Kovalenko A.E. Surgical treatment of thyroid diseases in pregnant women / A.E. Kovalenko, A.V. Omel'chuk, Ju.V. Davydova // Hazeta «Zdorov"ya Ukrayiny». Tematychnyy nomer «Endokrynolohiya», zhovten' 2009 r. — S. 40–42.
Aoki Y. Serum TSH and total T4 in the United States population and their association with participant characteristics: National Health and Nutrition Examination Survey (NHANES 1999–2002) / Y. Aoki, R.M. Belin, R. Clickner et al.// Thyroid. – 2007. – №17. – Р. 1211–1223.
Pan'kiv V.I. The practical thyroidology / V.I. Pan'kiv. – Donets'k: Vydavets' Zaslavs'kyy O.Yu., 2011. — 224 s
Muravleva O. V. The prevalence of the pathology of the thyroid gland in the Poltava region in the post-Chernobyl period and ways of its prevention / O. V. Muravleva, N. N. Rjabushko, L. E. Bobyreva //Odes'kij medichnij zhurnal. – 2004. – № 5. – S. 96-98.
Bobyr'ova L. Ye. Regional features of iodine deficiency disorders in Poltava region and their prevention / L. Ye. Bobyr'ova, O. V. Muravleva // Yoddefitsytni zakhvoryuvannya na Poltavshchyni – 2005: Oblasna naukovo-praktychna konferentsiya 26 travnya 2005 r.: mater. – Poltava, 2005.– S. 5–22.
Muravl'ova O. V. Features of clinical course and complex treatment of autoimmune thyroiditis: avtoreferat dys. na zdobuttya nauk. stupenya kand. med. nauk. / O. V. Muravl'ova; In-t problem endokrynnoyi patolohiyi im. V. Ya. Danylevs'koho AMN Ukrayiny. – Kh., 2006. – 20 s.
Ryabushko M. M. Treatment-and-prophylactic effectiveness of natural sorbent and antioxidants in long-term intake of fluoride (experimental clinical research): avtoreferat dys. na zdobuttya nauk. stupenya kand. med. nauk. / M. M. Ryabushko – K., 2002. – 20 s.
Zimmermann M. B. Iodine deficiency in industrialised countries [Text] / M. B. Zimmermann // Proc Nutr Soc. – 2009. – № 8. – P. 1–11.
Bobyr'ova L. Ye. Epidemiological studies of radiation-induced thyroid pathology in Poltava, Zhytomyr regions and Ukraine in general in the post-Chernobyl period / L. Ye. Bobyr'ova // «Medyko-henetychni ta ekolohichni problemy Chornobyl's'koyi katastrofy cherez 15 rokiv», mater. Oblasnoyi naukovo-praktychnoyi konferentsiyi, 19 kvitnya 2002 roku. – Poltava, 2001. – S. 4-14.
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