Reasons for the prescription of natural remedies in the treatment of autoimmune thyroiditis with different degrees of hypothyroidism

Main Article Content

N.Ye. Barabash
Yе.V. Simonova
T.M. Tykhonova
O.М. Nechvohlod
O.V. Shvets

Abstract

Background. Autoimmune thyroiditis is the most common cause of hypothyroidism. If the therapy of overt hypothyroidism by prescribing hormone replacement therapy is quite clear, then the problem of treating the patients with subclinical hypothyroidism remains open. The purpose of this study was to determine the effectiveness of using the combined natural drug Thyreos in the treatment of autoimmune thyroiditis without thyroid dysfunction, at the stage of subclinical hypothyroidism as monotherapy and in the comprehensive therapy of overt hypothyroidism in the combination with L-thyroxine. Materials and methods. Forty-nine patients aged 48.26 ± 13.52 years with autoimmune thyroiditis were examined. All individuals were divided into 3 groups. Group 1 included 20 patients with autoimmune thyroiditis without thyroid dysfunction, group 2 consisted of 16 people with newly diagnosed subclinical hypothyroidism, and group 3 included 13 patients, who previously received L-thyroxine therapy for overt hypothyroidism. All patients were prescribed Thyreos 1 capsule twice a day for a period of 3 months as monotherapy (groups 1 and 2) or in addition to hormone replacement therapy (group 3). Results. When evaluating complaints, it was found that after 3 months of taking the drug, weakness and rapid fatigue were observed in a significantly smaller number of patients in all three groups (p < 0.05). Complaints of dryness and hair loss in individuals of the first two groups (p < 0.05) were also probably less frequent after 3 months of therapy with Thyreos. As a result of treatment, dry skin was significantly reduced in patients of only the first examined group (p = 0.024). In people with newly diagnosed subclinical hypothyroidism, a significant dynamics of thyroid-stimulating hormone level was determined. In patients with overt hypothyroidism, the supplementation of Thyreos to L-thyroxine significantly reduced thyroid-stimulating hormone content and increased free thyroxine level without changing the dose of hormone replacement therapy. All examined individuals tolerated the drug well, without any adverse reactions. Conclusions. In the presence of subclinical and overt hypothyroidism on the background of autoimmune thyroiditis, the use of a combined natural remedy Thyreos is quite justified. The drug showed a clinically significant positive effect, which manifested itself in the improvement of well-being and hormonal status parameters of patients, both as monotherapy in subclinical hypothyroidism and in combination with L-thyroxine — in overt one. Preliminary results of Thyreos effect on the suppression of the autoimmune process in the thyroid gland need further clarification with the involvement of more patients and extension of treatment.

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How to Cite
Barabash, N., Y. Simonova, T. Tykhonova, O. Nechvohlod, and O. Shvets. “Reasons for the Prescription of Natural Remedies in the Treatment of Autoimmune Thyroiditis With Different Degrees of Hypothyroidism”. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine), vol. 16, no. 5, Aug. 2020, pp. 408-13, doi:10.22141/2224-0721.16.5.2020.212744.
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Original Researches

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