Сучасні досягнення клінічної патофізіології у вивченні патогенезу цукрового діабету 1-го і 2-го типу в людини

M.D. Tronko; K.P. Zak

doi:10.22141/2224-0721.15.6.2019.185403

PDF (Русский)

DOI: https://doi.org/10.22141/2224-0721.15.6.2019.185403

Keywords:

clinical pathophysiology, diabetes mellitus type 1 and 2 in a human, diagnosis, pathogenesis, review

M.D. Tronko

MD, PhD, Professor, Academician of NAS, Head of the State Institution “V.P. Komisarenko Institute of Endocrinology and Metabolism of the NAMS of Ukraine”, Vyshgorodska st., 69, Kyiv, 04114, Ukraine

http://orcid.org/0000-0001-7421-0981

K.P. Zak

MD, PhD, Professor, Head of the Laboratory of Hormonal regulation, State Institution “V.P. Komisarenko Institute of Endocrinology and Metabolism of the NAMS of Ukraine”, Vyshgorodska st., 69, Kyiv, 04114, Ukraine

http://orcid.org/0000-0001-5432-1107

Abstract

The review deals with the development and achievements in a new scientific direction in medicine studying the pathogenesis of various human diseases — clinical pathophysiology over the last decades. The latest low-traumatic intravital highly sensitive research methods used in pathophysiology for studying the important vital physiological and immunological processes in an organism of patients with type 1 and type 2 diabetes mellitus made it possible to show that the etiopathogenesis of these diseases in humans significantly differs from that in animals with experimental diabetes mellitus. This made it possible to obtain more accurate information about the causes and natural course of diabetes mellitus in humans that requires the development of new methods for its diagnosis, especially at the preclinical stage of development and to stimulate the development of more effective agents for the prevention and treatment of this disease.

How to Cite

Tronko, M., and K. Zak. “Current Advances in Clinical Pathophysiology in the Study of the Pathogenesis of Type 1 and Type 2 Diabetes Mellitus in Humans”. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine), vol. 15, no. 6, Dec. 2019, pp. 422-34, doi:10.22141/2224-0721.15.6.2019.185403.

Issue

Vol. 15 No. 6 (2019)

Section

Leading Article

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