Evaluation of Hypothalamic-Pituitary-Gonadal Axis in Men with Metabolic Syndrome and Androgen Deficiency Depending on Age

Main Article Content

S.I. Ismailov
Yu.M. Urmanova
I.F. Nabieva

Abstract

In this article authors carried out the literature review on this topic. For this reason authors noted that in obese men of reproductive age it’s necessary to study the level of hypothalamic-pituitary-gonadal axis disorders for further choice of correct replacement hormone therapy. In men with age-related androgen deficiency (at secondary hypogonadism) the stimulating therapy with chorionic gonadotropin can be the choice therapy as compared with androgen replacement therapy. In men with primary hypogonadism a lot of authors recommend to use androgen replacement therapy. In men with metabolic syndrome regardless of age it’s necessary to correct dyslipidemia and insulin resistance. Men with metabolic syndrome mostly have secondary hypogonadism.

Article Details

How to Cite
Ismailov, S., Y. Urmanova, and I. Nabieva. “Evaluation of Hypothalamic-Pituitary-Gonadal Axis in Men With Metabolic Syndrome and Androgen Deficiency Depending on Age”. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine), no. 1.41, Feb. 2012, pp. 92-97, doi:10.22141/2224-0721.0.1.41.2012.176815.
Section
Literature Review

References

Handelsman D.J., Zajac J.D. // Med. J. Aust. — 2004. — Vol. 180. — P. 529-535.

Bojesen A., Juul S., Gravholt C.H. // J. Clin. Endocrinol. Metab. — 2003. — Vol. 88. — P. 622-626.

Harman S.M., Metter E.J., Tobin J.D. et al. Longitudinal effects of ageing on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of Aging // J. Clin. Endocrinol. Metab. — 2001. — Vol. 86(2). — P. 724-731.

Vermeulin A., Kaufman J.M., Giagulli V.A. Influence of some biological indexes on sex hormone-binding globulin and androgen levels in ageing or obese males // J. Clin. Endocrinol. Metab. — 1996. — Vol. 81. — P. 1821-1826.

Morley J.E., Perry H.M. Andropause: an old concept in new clothing // Clinics in Geriatric Medicine. — 2003. — Vol. 19, № 3.

Swerdloff R.S. et al. // J. Clin. Endocrinol. Metab. — 2000. — Vol. 85. — P. 4500-4510.

Brambilla D.J. et al. // Clin. Endocrinol. (Oxf.). — 2007. — Vol. 67. — P. 853-862.

Bhasin S. et al. // J. Clin. Endocrinol. Metab. — 2006. — Vol. 91. — P. 1995-2010.

AACE. Endocr. Pract. — 2002. — Vol. 8. — P. 440-456.

Makshida N., Shah J., Yan G. et al. // J. Urology. — 2005. — Vol. 174. — P. 827-834.

Feldman I.R. Age trends in the level of serum testosterone and other hormones in middle-aged men: longitudinal results from the Massachusetts Male Aging study // J. Clin. Endocrinol. Metab. — 2002. — Vol. 87.

Калинченко С.Ю. Возрастной андрогенный дефицит (клиника, диагностика, лечение): Автореф. дис… д-ра мед. наук. — Москва, 2006. — 25 с.

Wynne F.X., Khalil R.A. Testosterone and coronary vascular tone // J. Endocrinological Invest. — 2003. — Vol. 26. — P. 181-186.

Shabsigh R., Rajfert A., Yassin A. The evolving role of testosterone in the treatment of erectile dysfunction // J. Clin. Pract. — 2006. — Vol. 60(9). — P. 1087-1092.

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