DOI: https://doi.org/10.22141/2224-0721.15.1.2019.158697

Main syndromes of hyperandrogenia in women: pathogenesis, differential diagnosis (literature review and own observation)

P.M. Liashuk, R.P. Liashuk

Abstract


Hyperandrogenic syndrome is a pathological condition caused by an excessive production of androgens by ovaries and/or adrenal glands or increased local tissue sensitivity to circulating androgens. This is the most common endocrinopathy in women. The importance of timely diagnosis of hyperandrogenic states is due to their consequences: androgen-dependent dermopathy, menstrual disorders, endocrine infertility, increased risk of non-pregnancy, preterm labor, gestational diabetes. The prevalence and possible consequences of hyperandrogenism in women of reproductive age predetermine the importance of timely differential diagnosis of the major syndromes of hyperandrogenic states — adrenogenital syndrome and polycystic ovary syndrome. Since the symptoms of these syndromes have much in common, based on the data of literature review and own observations, a differential diagnosis is supplemented and presented in the form of an original table that to some extent will help endocrinologists and gynecologists to distinguish between these pathological conditions.

Keywords


adrenogenital syndrome; polycystic ovaries; reproductive function; pathogenesis; differential diagnosis; review

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