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Background. Violation of bone mineral density as a cause of disability and mortality due to fractures, according to the data of World Health Organization, rank fourth in the world in terms of the prevalence after cardiovascular diseases, cancer and diabetes mellitus. The purpose is to study the frequency and structure of the main risk factors for osteoporosis and fractures in women with postmenopausal osteoporosis. Materials and methods. The structure and prevalence of major risk factors of osteoporosis and fractures were studied in 42 women with postmenopausal osteoporosis. Osteoporosis was verified by the lowenergy fracture and/or appropriate densitometry Tcriterion. A focused survey was conducted to identify the risk factors of osteoporosis and fractures in accordance with clinical guidelines and by using the FRAX (Fracture Risk Calculator). The indicators of bone mineral metabolism and the level of circulating 25(OH)D were evaluated. Results. An inadequate supply of vitamin D, previous fractures and impaired reproductive function were the most frequent factors. Also, other factors were determined, such as the somatic causes of secondary osteoporosis (diabetes mellitus, obesity, hypothyroidism), diseases of the gastrointestinal tract and those associated with the osteoporosis. Conclusions. The algorithm is developed to diagnose and monitor osteoporosis in postmenopausal women at the level of primary medical care.
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Leslie WD, Majumdar SR, Lix LM, et al. High fracture probability with FRAX usually indicates densitometric osteoporosis: implications for clinical practice. Osteoporos Int. 2012 Jan;23(1):391-7. doi: 10.1007/s00198-011-1592-3.
Binkley N, Bilezikian JP, Kendler DL, et al. Official positions of the International Society for Clinical Densitometry and Executive Summary of the 2005 Position Development Conference. J Clin Densitom. 2006 Jan-Mar;9(1):4-14. doi: 10.1016/j.jocd.2006.05.002.
Kanis JA, Compston J, Cooper C, et al. The burden of fractures in the European Union in 2010. Osteoporos Int. 2012;23(1):57.
Kanis JA, Burlet N, Cooper C, et al. European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Osteoporos Int. 2008 Apr;19(4):399-428. doi: 10.1007/s00198-008-0560-z.
Holick MF, Binkley NC, Bischoff-Ferrari HA, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2011 Jul;96(7):1911-30. doi: 10.1210/jc.2011-0385.
Camacho PM, Petak SM, Binkley N, et al. American Association of Clinical Endocrinologists and American College of Endocrinology Clinical Practice guidelines for the diagnosis and treatment of postmenopausal osteoporosis. Endocr Pract. 2016 Sep;22(9):1111-8. doi: 10.4158/EP161435.ESGL.
Kovalenko VN, Povoroznyuk VV, Bortkevych OP, et al. Guidance for diagnostic, prevention and management of osteoporosis in postmenopausal women. Ukraïnsʹkij revmatologìcnij zurnal. 2009;(37):23-39. (in Russian).