The psychological state of children with syndrome of biologically inactive growth hormone
Background. The purpose was to study the psychological state of children with syndrome of biologically inactive growth hormone (SBIGH) and to evaluate the effect of specific growthstimulating therapy on improving the psychosocial adaptation of patients in society. Materials and methods. The study involved 46 children with SBIGH during puberty, including 30 boys and 16 girls. To investigate the psychological state of children with SBIGH, the patients were examined on the scale of depression selfesteem prior to the application of specific hormonal growthstimulating therapy and 6 months after continuous treatment. The control group consisted of 25 healthy children. Results. Our testing showed that 72 % of the respondents with SBIGH had a predisposition to depression, while among healthy children, this index was only 24 %. When the treatment was initiated using recombinant growth hormone and gonadotropinreleasing hormone analogues for 6 consecutive months in children with short stature, and when a higher rate of growth in them was reached, the susceptibility to depression remained only in 27.6 % of patients. Conclusions. Short stature among children with SBIGH results in a lower selfesteem and manifestations of depression. The treatment of children using recombinant growth hormone with motivation for a positive growth effect significantly improves their psychological state and adaptation in society. It is recommended to conduct a questionnaire survey of patients with SBIGH on the scale of depression selfesteem, and in the presence of manifestations of a tendency to depressive state, it is advisable to consult with a medical psychologist or specialist in psychosomatic medicine.
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Salinero-Fort MÁ, Gómez-Campelo P, Bragado-Alvárez C, et al. Health-related quality of life of latin-american immigrants and spanish-born attended in spanish primary health care: socio-demographic and psychosocial factors. PLoS One. 2015 Apr 2;10(4):e0122318. doi: 10.1371/journal.pone.0122318.
Geisler A, Lass N, Reinsch N, et al. Quality of life in children and adolescents with growth hormone deficiency: association with growth hormone treatment. Horm Res Paediatr. 2012;78(2):94-9. doi: 10.1159/000341151.
Soltakhanov EM, Kostrova IB, Arslanbekova ACh. Diagnosis and treatment of growth hormone deficiency in the early childhood. Vestnik Dagestanskoj gosudarstvennoj medicinskoj akademii. 2018;(26):67-70. (in Russian).
Richmond E, Rogol AD. Treatment of growth hormone deficiency in children, adolescents and at the transitional age. Best Pract Res Clin Endocrinol Metab. 2016 Dec;30(6):749-755. doi: 10.1016/j.beem.2016.11.005.
Smuel K, Kauli R, Lilos P, Laron Z. Growth, development, puberty and adult height before and during treatment in children with congenital isolated growth hormone deficiency. Growth Horm IGF Res. 2015 Aug;25(4):182-8. doi: 10.1016/j.ghir.2015.05.001.
Chaban OS. Patient with depression in the practice of a family doctor. Biblioteka simejnogo likarja ta simejnoi' medsestry. 2011;(28):59-65. (in Ukrainian).
Ministry of Нealth of Ukraine. Order on February 2, 2009 № 55. On Adoption of Treatment Protocols for Children with Endocrine Diseases. Available from: http://zakon.rada.gov.ua/rada/show/v0055282-09?lang=en. Accessed: February 2, 2009. (in Ukrainian).
Blunck W. Pädiatrische Endokrinologie. München: Urban & Schwarzenberg; 1977. 250 p. (in German).
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