Epidemiology and socio-economic features of myocardial infarction and stroke in patients with type 2 diabetes mellitus

Z.G. Krushinska, T.Yu. Yuzvenko, V.I. Pankiv


Background. The purpose was to study epidemiology and socio-economic features of myocardial infarction (МI) and stroke in patients with the type 2 diabetes mellitus (DM). Materials and methods. Patients were divided into 3 groups: first group consisted of all patients with type 2 DM included in the research (n = 1,999), second group — of patients (n = 201) with DM from the first group with МI, third group were patients with DM from the first group with stroke (n = 155). Results. Significant differences were established between the incidence of DM and the incidence of МI and stroke depending on the sex of patients. The average age of DM patients with МI and stroke was higher as compared to the general population of DM patients. Majority of patients was presented by the socially vulnerable people, who do not have the financial opportunity to get medical care, in particular therapy adequate for their state, present complications and concomitant pathology. Conclusions. Repeated МI was registered in 3 % of patients with DM; more than three times often, the recurrent stroke (9.7 %) occurred, more often among women (12.2 vs 6.2 % in men). A proportion of patients with МI among those with stroke is 2 times greater than the same index among all patients with DM (20.7 and 10.1 %, respectively).


type 2 diabetes mellitus; myocardial infarction; stroke


International Diabetes Federation. IDF Diabetes Atlas. 8th ed. Brussels: IDF; 2017.

Introduction: Standards of Medical Care in Diabetes-2018. Diabetes Care. 2018;41(Suppl 1):S1-S2. doi: 10.2337/dc18-Sint01.

Zheng Y, Ley SH, Hu FB. Global aetiology and epidemiology of type 2 diabetes mellitus and its complications. Nat Rev Endocrinol. 2018;14(2):88-98. doi: 10.1038/nrendo.2017.151.

Guariguata L, Whiting DR, Hambleton I, Beagley J, Linnenkamp U, Shaw JE. Global estimates of diabetes prevalence for 2013 and projections for 2035. Diabetes Res Clin Pract. 2014 Feb;103(2):137-49. doi: 10.1016/j.diabres.2013.11.002.

Low WCC, Hess CN, Goldfine AB, Goldfine AB. Clinical update: cardiovascular disease in diabetes mellitus: atherosclerotic cardiovascular disease and heart failure in type 2 diabetes mellitus – mechanisms, management, and clinical considerations. Circulation. 2016 Jun 14;133(24):2459-502. doi: 10.1161/CIRCULATIONAHA.116.022194.

Benjamin EJ, Blaha MJ, Chiuve SE, et al. Heart disease and stroke statistics-2017 update: a report from the American Heart Association. Circulation. 2017 Mar 7;135(10):e146-e603. doi: 10.1161/CIR.0000000000000485.

Collaboration Emerging Risk Factors, Sarwar N, Gao P, Seshasai SR, et al. Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies. Lancet. 2010 Jun 26;375(9733):2215-22. doi: 10.1016/S0140-6736(10)60484-9.

D’Agostino RB, Hamman RF, Karter AJ, Mykkanen L, Wagenknecht LE, Haffner SM. Insulin Resistance Atherosclerosis Study I. Cardiovascular disease risk factors predict the development of type 2 diabetes: the insulin resistance atherosclerosis study. Diabetes Care. 2004 Sep;27(9):2234-40. doi: 10.2337/diacare.27.9.2234.

Odegaard AO, Jacobs DR, Sanchez OA, Goff DC, Reiner AP, Gross MD. Oxidative stress, inflammation, endothelial dysfunction and incidence of type 2 diabetes. Cardiovasc Diabetol. 2016 Mar 24;15:51. doi: 10.1186/s12933-016-0369-6.

Shu L, Chan KHK, Zhang G, et al. Shared genetic regulatory networks for cardiovascular disease and type 2 diabetes in multiple populations of diverse ethnicities in the United States. PLoS Genet. 2017 Sep 28;13(9):e1007040. doi: 10.1371/journal.pgen.1007040.

Alberti KG, Eckel RH, Grundy SM, et al. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation. 2009 Oct 20;120(16):1640-5. doi: 10.1161/CIRCULATIONAHA.109.192644.

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