Main Article Content
Background. In Ukraine, there is a clear increase in the number of patients with different thyroid pathology. Indicators of the prevalence and morbidity vary in different regions of the country depending on the influence of environment factors and their combination. One of the known factors is Chornobyl accident, but the growth of thyroid pathology in least polluted areas indicates the need for a more detailed study of this problem. The purpose was to conduct an analysis on the prevalence and morbidity of thyroid pathology among the population of Kyiv region for 2007–2017. Materials and methods. Data of annual reports of medical institutions in Kyiv region for 2007–2017 were analyzed. Statistical analysis was carried out with the help of the program package Windows Office Exсel 2016 and IBM SPSS Statistics 23.0. Results. In the structure of thyroid pathology among the population of Kyiv region in 2017, the proportion of thyroiditis was 11.2 %, hypothyroidism — 4.6 %, hyperthyroidism — 2.1 %. In women, thyroiditis occurred 9.7 times more often than in men, hypothyroidism — 8.3 times and hyperthyroidism — 5.3 times. Reliable data on increased prevalence of thyroiditis were found in the region (thyroiditis — by 1.9 times (p < 0.01), hypothyroidism — 2.1 times (p < 0.01), hyperthyroidism — 1.7 times (p < 0.01)) and in Ukraine (thyroiditis — by 2.5 times (p < 0.01), hypothyroidism — 1.7 times (p < 0.01), hyperthyroidism — 1.5 times (p < 0.01)). According to the prognostic models, in the next five years, an increase is expected in the prevalence of thyroiditis, hypothyroidism and hyperthyroidism in the region, which may be determined by the negative effects of exogenous and endogenous factors. Conclusions. The steady increase in the prevalence and morbidity of thyroid pathology in the polluted and least polluted regions of Ukraine after the Chornobyl Nuclear Power Plant accident, an increase in the proportion of thyroiditis, hypo- and hyperthyroidism over the last decade, the predicted growth of this pathology over the next 5 years suggests the need to analyze the causes and measures of their prevention in practice of family doctors and endocrinologists.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Our edition uses the copyright terms of Creative Commons for open access journals.
Authors, who are published in this journal, agree with the following terms:
- The authors retain rights for authorship of their article and grant to the edition the right of first publication of the article on a Creative Commons Attribution 4.0 International License, which allows others to freely distribute the published article, with the obligatory reference to the authors of original works and original publication in this journal.
- Directing the article for the publication to the editorial board (publisher), the author agrees with transmitting of rights for the protection and using the article, including parts of the article, which are protected by the copyrights, such as the author’s photo, pictures, charts, tables, etc., including the reproduction in the media and the Internet; for distributing; for the translation of the manuscript in all languages; for export and import of the publications copies of the writers’ article to spread, bringing to the general information.
- The rights mentioned above authors transfer to the edition (publisher) for the unlimited period of validity and on the territory of all countries of the world.
- The authors guarantee that they have exclusive rights for using of the article, which they have sent to the edition (publisher). The edition (the publisher) is not responsible for the violation of given guarantees by the authors to the third parties.
- The authors have the right to conclude separate supplement agreements that relate to non-exclusive distribution of their article in the form in which it had been published in the journal (for example, to upload the work to the online storage of the journal or publish it as part of a monograph), provided that the reference to the first publication of the work in this journal is included.
- The policy of the journal permits and encourages the publication of the article in the Internet (in institutional repository or on a personal website) by the authors, because it contributes to productive scientific discussion and a positive effect on efficiency and dynamics of the citation of the article.
Kravchenko VI. Iodine deficiency as a cause of high prevalence of thyroid pathology in the population of regions affected by the chernobyl accident. Zhurnal NAMN Ukrai'ny. 2016;22(2):222-229 (in Ukrainian).
Zablotska LB, Bogdanova TI, Ron E, et al. A cohort study of thyroid cancer and other thyroid diseases after the Chornobyl accident: dose-response analysis of thyroid follicular adenomas detected during first screening in Ukraine (1998-2000). Am J Epidemiol. 2008 Feb 1;167(3):305-12. doi: 10.1093/aje/kwm301.
Fuzik MM, Prysyazhnyuk AY, Shibata Y, et al. Age and gender patterns of thyroid cancer incidence in Ukraine depending on thyroid radiation doses from radioactive iodine exposure after the Chornobyl NPP accident. Probl Radiac Med Radiobiol. 2013;(18):144-55.
Kaminskyi OV, Kopylova OV, Afanasyev DE, Pronin OV. Non-cancer thyroid and other endocrine disease in children and adults exposed to ionizing radiation after the ChNPP accident. Problems of radiation medicine and radiobiology. 2015;20:341-355. (in Ukrainian).
Davis S, Kopecky KJ, Hamilton TE, Onstad L; Hanford Thyroid Disease Study Team. Thyroid neoplasia, autoimmune thyroiditis, and hypothyroidism in persons exposed to iodine 131 from the Hanford nuclear site. JAMA. 2004 Dec 1;292(21):2600-13. doi: 10.1001/jama.292.21.2600.
Agate L, Mariotti S, Elisei R, et al. Thyroid autoantibodies and thyroid function in subjects exposed to Chernobyl fallout during childhood: evidence for a transient radiationinduced elevation of serum thyroid antibodies without an increase in thyroid autoimmune disease. J Clin Endocrinol Metab. 2008 Jul;93(7):2729-36. doi: 10.1210/jc.2008-0060.
Buzunov VA, Pirogova EA, Krasnikova LI, Tereshchenko VM, Vojchulene YuV. Epidemiology of non-neoplastic effects of ionizing radiation. Zhurnal NAMN Ukrai'ny. 2006;12(1):174-84. (in Russian).
Larin OS, Pankiv VI, Selivanenko MI, Grachova OO. Analysis of the endocrinology care of Ukraine in 2010 and prospects for the development of medical care for patients with endocrine disorders. Mìžnarodnij endokrinologìčnij žurnal. 2011;(35):10-18. (in Ukrainian).