Antihyperglycemic therapy of elderly and senile patients in real clinical practice

Main Article Content

V.I. Pankiv


The lecture deals with the topical issues of treating elderly and senile patients with diabetes mellitus (DM). The number of such people with type 2 DM is steadily increasing. The management of this category of patients should be individual and include adequate correction of hyperglycemia to prevent microvascular complications, as well as hypoglycemic episodes, to reduce cardiovascular mortality and to maintain the quality of life. The basic data about clinical features of DM and application of antihyperglycemic preparations in elderly and senile patients are presented. Special attention is paid to the target levels of glycemic control.

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How to Cite
Pankiv, V. “Antihyperglycemic Therapy of Elderly and Senile Patients in Real Clinical Practice”. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine), vol. 14, no. 2, May 2018, pp. 199-04, doi:10.22141/2224-0721.14.2.2018.130567.
To practicing Endocrinologists


Inzucchi SE, Bergenstal RM, Buse JB, et al. Management of hyperglycemia in type 2 diabetes, 2015: a patient-centered approach: update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetologia. 2015 Mar;58(3):429-42. doi: 10.1007/s00125-014-3460-0.

Ma F, Wu T, Miao R, Xiao YY, Zhang W, Huang G. Conversion of mild cognitive impairment to dementia among subjects with diabetes: a population-based study of incidence and risk factors with five years of follow-up. J Alzheimers Dis. 2015;43(4):1441-9. doi: 10.3233/JAD-141566.

Solini A, Penno G, Bonora E, et al. Age, renal dysfunction, cardiovascular disease, and antihyperglycemic treatment in type 2 diabetes mellitus: findings from the Renal Insufficiency and Cardiovascular Events Italian Multicenter Study. J Am Geriatr Soc. 2013 Aug;61(8):1253-61. doi: 10.1111/jgs.12381.

Huang ES, Laiteerapong N, Liu JY, John PM, Moffet HH, Karter AJ. Rates of complications and mortality in older diabetes patients: the diabetes and aging study. JAMA Intern Med. 2014 Feb 1;174(2):251-8. doi: 10.1001/jamainternmed.2013.12956.

Lind M, Olsson M, Rosengren A, Svensson AM, Bounias I, Gudbjörnsdottir S. The relationship between glycaemic control and heart failure in 83,021 patients with type 2 diabetes. Diabetologia. 2012 Nov;55(11):2946-53. doi: 10.1007/s00125-012-2681-3.

Goto A, Arah OA, Goto M, Terauchi Y, Noda M. Severe hypoglycaemia and cardiovascular disease: systematic review and meta-analysis with bias analysis. BMJ. 2013 Jul 29;347:f4533. doi: 10.1136/bmj.f4533.

Avery L, Flynn D, van Wersch A, Sniehotta FF, Trenell MI. Changing physical activity behavior in type 2 diabetes: a systematic review and meta-analysis of behavioral interventions. Diabetes Care. 2012 Dec;35(12):2681-9. doi: 10.2337/dc11-2452.

Launer LJ, Miller ME, Williamson JD, et al. Effects of intensive glucose lowering on brain structure and function in people with type 2 diabetes (ACCORD MIND): a randomised open-label substudy. Lancet Neurol. 2011 Nov;10(11):969-77. doi: 10.1016/S1474-4422(11)70188-0.

Kodama S, Horikawa C, Yoshizawa S, et al. Body weight change and type 2 diabetes. Epidemiology. 2013 Sep;24(5):778-9. doi: 10.1097/EDE.0b013e31829f6c31.

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