Effective variant of type 2 diabetes mellitus treatment
Keywords:type 2 diabetes mellitus, dyslipidemia, Ferment S6
Background. The purpose was to evaluate the efficiency of phytoextract Ferment S6 as a part of comprehensive therapy in patients with type 2 diabetes mellitus (DM). Materials and methods. Thirty patients with type 2 DM and dyslipidemia were under observation. Duration of type 2 DM was from 8 to 25 years, average age of patients — 39.5 ± 6.7 years. All patients received Ferment S6 phytoextract (one capsule after breakfast) in addition to combination treatment. Duration of follow-up was 3 months. Patients underwent laboratory and instrumental examination. Results. As a result of Ferment S6 phytoextract addition to the comprehensive DM therapy, there was a positive dynamics of somatic signs. The improvement of carbohydrate and lipid exchanges is marked, and also indexes of the functional state of the liver. The clinical safety of preparation was determined on the basis of subjective symptoms reported by patients (in the process of supervision — 2 visits during three months), objective data, and laboratory indexes in dynamics (at the beginning of research and on a final visit). The analysis of tolerability of the drug during comprehensive therapy showed that in 100 % of cases it was good. Conclusions. After treatment with inclusion of phytoextract Ferment S6, there was marked a decrease in subjective asthenic, somatic and vegetative disorders as a reduction in the degree of severity of headache, irritability, general weakness, improvement of quality of life. The most significant changes were: an increase in working capacity and tolerance to physical activity, which increased the adherence of patients to the observance of a lifestyle with type 2 DM. Phytoextract Ferment S6 is well tolerated by patients and does not cause side effects with prolonged use.
American Diabetes Association. Standards of medical care in diabetes - 2017: Promoting Health and Reducing Disparities in Populations. Diabetes Care. 2017 Jan; 40(Suppl 1):S6-S10. doi: 0.2337/dc17-S004.
Garber AJ, Abrahamson MJ, Barzilay JI, et al. Consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the comprehensive type 2 diabetes management algorithm – 2017 executive summary. Endocr Pract. 2017 Feb;23(2):207-238. doi: 10.4158/EP161682.CS.
Cho NH, Kirigia J, Mbanya JC, et al, editors. IDF Diabetes Atlas - 8thEdition. 2017. Available from: http://www.diabetesatlas.org/resources/2017-atlas.html.
Bergmark BA, Bhatt DL, Braunwald E, et al. Risk Assessment in Patients With Diabetes With the TIMI Risk Score for Atherothrombotic Disease. Diabetes Care. 2018 Mar;41(3):577-585. doi: 10.2337/dc17-1736.
Basu S, Raghavan S, Deborah J, Wexler DJ. Characteristics Associated With Decreased or Increased Mortality Risk From Glycemic Therapy Among Patients With Type 2 Diabetes and High Cardiovascular Risk: Machine Learning Analysis of the ACCORD Trial. Diabetes Care. 2018 Mar;41(3):604-612. doi: 10.2337/dc17-2252.
Nielsen J, Hulman A, Witte DR. Spousal cardiometabolic risk factors and incidence of type 2 diabetes: a prospective analysis from the English Longitudinal Study of Ageing. Diabetologia. 2018 Mar 8. doi: 10.1007/s00125-018-4587-1. [Epub ahead of print].
Huo L, Magliano DJ, Rancière F, et al. Impact of age at diagnosis and duration of type 2 diabetes on mortality in Australia 1997-2011. Diabetologia. 2018 May;61(5):1055-1063. doi: 10.1007/s00125-018-4544-z.
Wilmot EG, Edwardson CL, Achana FA, et al. Sedentary time in adults and the association with diabetes, cardiovascular disease and death: systematic review and meta-analysis. Diabetologia. 2012 Nov;55(11):2895-905. doi: 10.1007/s00125-012-2677-z.
Raman R, Gupta A, Krishna S, Kulothungan V, Sharma T. Prevalence and risk factors for diabetic microvascular complications in newly diagnosed type II diabetes mellitus. Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular Genetic Study (SN-DREAMS, report 27). J Diabetes Complications. 2012 Mar-Apr;26(2):123-8. doi: 10.1016/j.jdiacomp.2012.02.001.
Copyright (c) 2020 I.V. Cherniavska, O.V. Zemlianitsyna, I.P. Romanova, N.O. Kravchun
This work is licensed under a Creative Commons Attribution 4.0 International License.
Our edition uses the copyright terms of Creative Commons for open access journals.
Authors, who are published in this journal, agree with the following terms:
- The authors retain rights for authorship of their article and grant to the edition the right of first publication of the article on a Creative Commons Attribution 4.0 International License, which allows others to freely distribute the published article, with the obligatory reference to the authors of original works and original publication in this journal.
- Directing the article for the publication to the editorial board (publisher), the author agrees with transmitting of rights for the protection and using the article, including parts of the article, which are protected by the copyrights, such as the author’s photo, pictures, charts, tables, etc., including the reproduction in the media and the Internet; for distributing; for the translation of the manuscript in all languages; for export and import of the publications copies of the writers’ article to spread, bringing to the general information.
- The rights mentioned above authors transfer to the edition (publisher) for the unlimited period of validity and on the territory of all countries of the world.
- The authors guarantee that they have exclusive rights for using of the article, which they have sent to the edition (publisher). The edition (the publisher) is not responsible for the violation of given guarantees by the authors to the third parties.
- The authors have the right to conclude separate supplement agreements that relate to non-exclusive distribution of their article in the form in which it had been published in the journal (for example, to upload the work to the online storage of the journal or publish it as part of a monograph), provided that the reference to the first publication of the work in this journal is included.
- The policy of the journal permits and encourages the publication of the article in the Internet (in institutional repository or on a personal website) by the authors, because it contributes to productive scientific discussion and a positive effect on efficiency and dynamics of the citation of the article.