Clinical efficiency of aerobic exercises in the young patients with type 1 diabetes mellitus

Authors

  • P.O. Goldobin Private Сonsultant in Diabetes Mellitus, Kyiv, Ukraine
  • D.V. Shorikova State Higher Education Institution of Ukraine “Bukovinian State Medical University”, Chernivtsi, Ukraine

DOI:

https://doi.org/10.22141/2224-0721.14.1.2018.127085

Keywords:

type 1 diabetes mellitus, aerobic exercises, glycemic profile, insulin sensitivity, quality of life

Abstract

Background. The purpose of the study is to investigate the effect of regular aerobic physical exercises with 6-point intensity by Borg scale on glycemic profile, insulin sensitivity, and quality of life of patients with type 1 diabetes mellitus (DM). Materials and methods. The data from 42 patients with type 1 DM were analyzed. There were 20 women and 22 men aged 18 to 35 years (mean age 25.3 ± 7.9 years). The level of glycemia and glycated hemoglobin was estimated. The Medical Outcomes Study Short Form 36 questionnaire was used to assess the quality of life. Results. It has been shown that aerobic exercises can significantly modify the clinical course of type 1 DM and change the quality of life. After 30 days of regular aerobic exercises, the mean daily dose of ultra-short-acting insulin was decreased by 25.4 % versus baseline (p < 0.05). It was found that sensitivity to insulin after regular aerobic exercises was increased by 42.0 % and became 0.60 U per 1 bread unit (BU) by the end of the observation versus 1.03 U per 1 BU before the study. Also, regular physical activity was associated with the decrease in glycated hemoglobin content by 1.5 %. It has been established that regular aerobic exercises contri­buted to the significant (p < 0.05) increase in the quality of life according to all the scales which form physical and psychological components of health (physical functioning, role-physical functioning, bodily pain, general health, role-emotional functioning, vitality, mental health, social functioning) versus baseline that was accompanied by increase in emotional stability and workability. Conclusions. Regular aerobic exercises had the positive impact on the clinical symptoms of type 1 DM, resulted in improved glycemic profile, increased insulin sensitivity and quality of life of patients.

References

UN Resolution on diabetes mellitus. Sakharni Diabet. 2007;1:2-3. (in Russian)

Mayorov AYu, Melnikova OG, Filippov YuI. Self-monitoring of blood glucose: a mainstay of effective diabetes treatment. Effektivnaya farmakoterapiya. 2013;35:46-57. (in Russian)

Sato K, Nishijima T, Yokokawa T, Fujita S. Acute bout of exercise induced prolonged muscle glucose transporter-4 translocation and delayed counter-regulatory hormone response in type 1 diabetes. PLoS One. 2017 Jun 1;12(6):e0178505. doi: 10.1371/journal.pone.0178505.

Falkowski B, Chudziński M, Jakubowska E, Duda-Sobczak A. Association of olfactory function with the intensity of self-reported physical activity in adults with type 1 diabetes. Pol Arch Intern Med. 2017 Aug 9;127(7-8):476-480. doi: 10.20452/pamw.4073.

Jewiss D, Ostman C, King N, Smart NA. Clinical Outcomes to Exercise Training in Type 1 Diabetes: A Systematic Review and Meta-Analysis. Diabetes Res Clin Pract. 2017 Dec 6. pii: S0168-8227(17)31108-7. doi: 10.1016/j.diabres.2017.11.036.

Codella R, Terruzzi I, Luzi L. Why should people with type 1 diabetes exercise regularly? Acta Diabetol. 2017 Jul;54(7):615-630. doi: 10.1007/s00592-017-0978-x.

Delamater AM, de Wit M, McDarby V. ISPAD Clinical Practice Consensus Guidelines 2014. Psychological care of children and adolescents with type 1 diabetes. Pediatr Diabetes. 2014 Sep;15 Suppl 20:232-44. doi: 10.1111/pedi.12191.

Lohse Z, Knorr S, Bytoft B, et al. Differential effects of age and sex on insulin sensitivity and body composition in adolescent offspring of women with type 1 diabetes: results from the EPICOM study. Diabetologia. 2018 Jan;61(1):210-219. doi: 10.1007/s00125-017-4458-1.

Al-Lahham Y, Mendes AK, Souza EM. Interleukin-18 (rs187238) and glucose transporter 4 (rs5435) polymorphisms in Euro-Brazilians with type 1 diabetes. Genet Mol Res. 2017 Sep 21;16(3). doi: 10.4238/gmr16039755.

Tikkanen-Dolenc H, Wadén J, Forsblom C, et al. Physical Activity Reduces Risk of Premature Mortality in Patients With Type 1 Diabetes With and Without Kidney Disease. Diabetes Care. 2017 Dec;40(12):1727-1732. doi: 10.2337/dc17-0615.

Ware JE, Snow KK, Kosinski M, et al. SF-36 Health Survey. Manual and interpretation guide. 2nd ed. Boston: The Health Institute, New England Medical Center; 1997. 28 p.

Yates T, Davies MJ. Physical activity and Type 1 diabetes: an underused therapy. Diabet Med. 2017 Nov;34(11):1498-1499. doi: 10.1111/dme.13445.

Downloads

Issue

Vol. 14 No. 1 (2018)

Section

Original Researches

License

Copyright (c) 2020 P.O. Goldobin, D.V. Shorikova

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Our edition uses the copyright terms of Creative Commons for open access journals.

Authors, who are published in this journal, agree with the following terms:

  1. The authors retain rights for authorship of their article and grant to the edition the right of first publication of the article on a Creative Commons Attribution 4.0 International License, which allows others to freely distribute the published article, with the obligatory reference to the authors of original works and original publication in this journal.
  2. Directing  the article for the publication to the editorial board (publisher), the author agrees with transmitting of rights for the protection and using the article, including parts of the article, which are protected by the copyrights, such as the author’s photo, pictures, charts, tables, etc., including the reproduction in the media and the Internet; for distributing; for the translation of the manuscript in all languages; for export and import of the publications copies of the writers’ article to spread, bringing to the general information.
  3. The rights mentioned above authors transfer to the edition (publisher) for the unlimited period of validity and on the territory of all countries of the world.
  4. The authors guarantee that they have exclusive rights for using of the article, which they have sent to the edition (publisher). The edition (the publisher) is not responsible for the violation of given guarantees by the authors to the third parties.
  5. The authors have the right to conclude separate supplement agreements that relate to non-exclusive distribution of their article in the form in which it had been published in the journal (for example, to upload the work to the online storage of the journal or publish it as part of a monograph), provided that the reference to the first publication of the work in this journal is included.
  6. The policy of the journal permits and encourages the publication of the article in the Internet (in institutional repository or on a personal website) by the authors, because it contributes to productive scientific discussion and a positive effect on efficiency and dynamics of the citation of the article.