Screening of abdominal obesity and diabetes mellitus in women with oncological diseases

N.O. Pertseva, M.K. Rokutova, V.V. Melnik

Abstract


Background. The purpose of the study was to assess the presence of excess body weight, abdominal obesity (AO), and type 2 diabetes mellitus (DM) in oncological diseases in women of young and middle age. Materials and methods. 32 outpatient women aged 31 to 59 years with a verified oncological disease were examined. Standard clinical methods of investigation, statistical processing of results by nonparametric statistics were used. Results. Cervical cancer was verified in 24 (75.0 %) persons, breast adenocarcinoma — in 5 (15.6 %), rectal cancer — in 3 (9.4 %) patients. Elevated body mass index was detected in 24 (75.0 %) women: excess body weight — in 11 (34.4%), AO stage I — in 8 (25.0%), stage II — in 5 persons (15.6 %). Overweight or AO were detected in 30 (93.8 %) patients according to waist-to-height ratio. Type 2 DM was detected only in 2 patients (6.3 %). A heredity in oncopathology was recorded in half of women, of them for AO — in 8 (25.0 %), for type 2 DM — in 5 (15.6 %) patients. A direct correlation was established between heredity in oncological disease and body weight (r = 0.62, p < 0.01), waist circumference (r = 0.61, p < 0.01), body mass index (r = 0.66, p < 0.01), waist-to-height ratio (r = 0.49, p <0.05), waist circumference/hip circumference ratio (r = 0.41, p < 0.01). Conclusions. Overweight and obesity are common among women with cancer, especially, with cervical cancer. Correlation between increased anthropometric indicators and a family history of oncological diseases among women was noted. For comprehensive diagnosis of overweight, in addition to the standard anthropometric indicators, the waist-to-height ratio should be used, as well as additional examinations to detect type 2 DM, insulin resistance, metabolic changes.


Keywords


abdominal obesity; oncological diseases; type 2 diabetes mellitus; insulin resistance; waist-to-height ratio; people of young and middle age

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DOI: https://doi.org/10.22141/2224-0721.13.8.2017.119275

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