Main Article Content
In the hypothalamus, there are nuclei of autonomic nervous system, as well endocrine system, and vitally important centers — of hunger, saturation, thermoregulation, sleep and wakefulness. Under the influence of traumatic brain injuries, neuroinfections and poisons, this complex integral system is often disturbed causing dysfunction of the hypothalamus. The prepared guidelines observe questions of the etiology, pathogenesis, clinical picture, diagnosis and treatment of hypothalamic dysfunction. In terms of therapy, a main emphasis is put on physiological approaches to the normalization of hypothalamic disorders. Particular attention is paid to the formulation of diagnosis according to the 10th revision of the International Statistical Classification of Diseases and Related Health Problems that has a significant importance for the regulation of statistical statements. Guidelines are intended for endocrinologists, neuropathologists, cardiologists, general practitioners and family doctors.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Our edition uses the copyright terms of Creative Commons for open access journals.
Authors, who are published in this journal, agree with the following terms:
- The authors retain rights for authorship of their article and grant to the edition the right of first publication of the article on a Creative Commons Attribution 4.0 International License, which allows others to freely distribute the published article, with the obligatory reference to the authors of original works and original publication in this journal.
- Directing the article for the publication to the editorial board (publisher), the author agrees with transmitting of rights for the protection and using the article, including parts of the article, which are protected by the copyrights, such as the author’s photo, pictures, charts, tables, etc., including the reproduction in the media and the Internet; for distributing; for the translation of the manuscript in all languages; for export and import of the publications copies of the writers’ article to spread, bringing to the general information.
- The rights mentioned above authors transfer to the edition (publisher) for the unlimited period of validity and on the territory of all countries of the world.
- The authors guarantee that they have exclusive rights for using of the article, which they have sent to the edition (publisher). The edition (the publisher) is not responsible for the violation of given guarantees by the authors to the third parties.
- The authors have the right to conclude separate supplement agreements that relate to non-exclusive distribution of their article in the form in which it had been published in the journal (for example, to upload the work to the online storage of the journal or publish it as part of a monograph), provided that the reference to the first publication of the work in this journal is included.
- The policy of the journal permits and encourages the publication of the article in the Internet (in institutional repository or on a personal website) by the authors, because it contributes to productive scientific discussion and a positive effect on efficiency and dynamics of the citation of the article.
Karachentsev YuI, editor. Ocherki klinicheskoj jendokrinologii [Essays of clinical endocrinology]. Kharkiv; 2011. 608 p. (In Russian).
Poline М, Glen V. Dokazatel'naja jendokrinologija [Evidential endocrinology]. Мoscow: GEOTAR-Media; 2008. 640 p. (In Russian).
Bodnar PM, editor. Endokrinologіja [Endocrinology]. Kyiv: Vyshcha Shkola; 2012. 460 p. (In Ukrainian)
Botsiurko VI, Bodnar PM, Mykhalchyshyn GP. Endokrinologіja u shemah і tablicjah [Endocrinology in charts and tables]. Ivano-Frankivsk; 2012. 117 p. (In Ukrainian).
Yron MC. Harrison Endocrinology. Hill Education; 2017. 633 p.
Shaikh MG. Hypothalamic dysfunction (hypothalamic syndromes). In: Oxford Textbook of Endocrinology and Diabetes. Wass JAH, Stewart PM, Amiel SA, Davies MC, editors. 2nd edition. doi: 10.1093/med/9780199235292.003.2181.
De Pontual L, Trochet D, Caillat-Zucman S, Abou Shenab OA, Bougneres P, Crow Y, Cunningham S, Esteva B, Heberle LC, Leger J, Pinto G, Polak M, Shafik MH, Straus C, Trang H, Munnich A, Lyonnet S, Desguerre I, Amiel J. Delineation of late onset hypoventilation associated with hypothalamic dysfunction syndrome. Pediatr Res. 2008;64(6):689-94. doi: 10.1203/PDR.0b013e318187dd0e.
Bougneres P, Pantalone L, Linglart A, Rothenbuhler A, Le Stunff C. Endocrine manifestations of the rapid-onset obesity with hypoventilation, hypothalamic, autonomic dysregulation, and neural tumor syndrome in childhood. J Clin Endocrinol Metabol. 2008;93(10):3971-80. doi: 10.1210/jc.2008-0238.
Ize-Ludlow D, Gray J, Sperling MA, Berry-Kravis EM, Milunsky JM, Farooqi IS, Rand CM, Weese-Mayer DE. Rapid onset obesity with hypothalamic dysfunction, hypoventilation, and autonomic dysregulation presenting in childhood. Pediatrics. 2007 Jul;120(1):e179-88. doi: 10.1542/peds.2006-3324.
Casanueva FF, Molitch ME, Schlechte JA, et al. Guidelines of the pituitary society for the diagnosis and management of prolactinomas. Clin Endocrinol. 2006 Aug;65(2): 265-273. doi: 10.1111/j.1365-2265.2006.02562.x.