Peripheral nervous system damage in hypothyroidism: current view on the problem (literature review)

О.А. Olenovych, N.V. Pashkovska, V.M. Pashkovskyy, I.V. Boyko

Abstract


The article presents the pathogenesis of polyneuropathy symptoms in patients with hypothyroidism, whereby the approaches to the pathogenetic therapy are substantiated. The article represents the most important aspects of hypothyroid polyneuropathy treatment according to the latest international guidelines and perspective scientific approaches to optimize the medical care for patients with this pathology.

Keywords


hypothyroidism; polyneuropathy; hypothyroid polyneuropathy

Full Text:

PDF

References


Antelava OA, Kasatkina LF, Gurkina GT, Radenska-Lopovok SG, Khitrov AN, Shtutman VZ, Nasonov EL. Differential diagnosis of muscle weakness. Rossijskij Medicinskij Zhurnal. 2004;14:15-8. (In Russian).

Balabolkin MI, Klebanova EM, Kreminskaia VM, authors. Differencial'naja diagnostika i lechenie jendokrinnyh zabolevanij. Rukovodstvo [Differential diagnosis and treatment of endocrine diseases. Manual]. Moscow: Meditsinskoe informatsionnoe agentstvo; 2008. 752 p. (In Russian).

Barinov AN, Akhmedzhanova LT, Makhinov KA. Algorithms for diagnosis and treatment of neuropathic pain in case of the peripheral nervous system lesion. Rossijskij Medicinskij Zhurnal. 2016;3:154-62. (In Russian).

Bol'shova OV, Muz' VA, Malinovs'ka TM. The application of alpha-lipoic acid in treatment of lipid disorders in children and adolescents with congenital hypothyroidism. Lіki Ukrajini. 2011;10(156):84-8. (In Ukrainian).

Vernigorodskii VS, Vlasenko MV, Fetisova NM. Neurovitan in complex treatment and rehabilitation of patients with hypothyroidism. Problemi endokrinnoї patologіji. 2011;2:36-40. (In Russian).

Vlasenko MV. Quality of life in patients with diabetes mellitus type 2 with metabolic neuropathy against the pathogenic therapy. Mezhdunarodnyi Endokrinologicheskii Zhurnal. 2013;1(49):1-4. (In Ukrainian). doi: 10.22141/2224-0721.1.49.2013.84052.

Grygorova IA, Tovazhnyanskaja EL. Features of the forming of hypothyroid polyneuropathy. Ukraїns'kij Nevrologіchnyi Zhurnal. 2008;2:67-72. (In Russian).

Kadykov AS, Shakhparonova NV. Neurometabolic treatment of patients with diseases of the nervous system. Possibilities of Actovegin administration. Rossijskij Medicinskij Zhurnal. 2008;26. (In Russian).

Korpachev VV, Borshchevskaia MI. Medicinal forms of thioctic acid. Problemi endokrinnoї patologіji. 2006;1:1-11. (In Russian).

Lutskii IS, Goncharova IaA, Evtushenko SK, Koktyshev IV, Lutskii EI, Kachanov RS. Comparison of the effectiveness of injectable and tablet forms of B vitamins in the treatment of polyneuropathies. Mezhdunarodnyi Nevrologicheskii Zhurnal. 2009;1(23):90-5. (In Russian).

Makar RD, Sandurs'ka MV. Hypothyroidism: conceptual aspects through the prism of time. Mezhdunarodnyi Endokrinologicheskii Zhurnal. 2009;1(19):124-31. (In Ukrainian).

Man'kovskii BN. Optimization of medicinal treatment of diabetic neuropathy. Zdorov'ia Ukraїni. 2007;8:58. (In Russian).

Matvіjenko IuO, Bozhenko NL, authors. Zapal'nі demієlіnіzujuchі polіnejropatії u zagal'nomedichnіj prakticі [Inflammatory demyelinating polyneuropathy in general medical practice]. Kyiv: TOV Liudi v bіlomu; 2014. 36 p. (In Ukrainian).

Mumentaler M, Bassetti K, Detvailer K, authors. Дифференциальный диагноз в неврологии: руководство по оценке, классификации и дифференциальной диагностике неврологических симптомов [Differential diagnosis in neurology: guidance on the evaluation, classification and differential diagnosis of neurologic symptoms]. Moscow: MEDpress-inform; 2010. 359 p. (In Russian).

Pan'kіv VІ. Hypothyroidism syndrome. Mezhdunarodnyi Endokrinologicheskii Zhurnal. 2012;5(45):174-91. (In Ukrainian).

Pashkovs'ka NV. Treatment of hypothyroidism according to modern clinical guidelines. Mezhdunarodnyiy endokrinologicheskiy zhurnal. 2016;6(78):48-58. (In Ukrainian). doi: 10.22141/2224-0721.6.78.2016.81860.

Silant'ev K. Klassicheskaja nevrologija: rukovodstvo po perifericheskoj nervnoj sisteme i hronicheskim bolevym sindromam [Classical neurology: a guide to the peripheral nervous system and chronic pain syndromes]. Volgograd: Panorama; 2006. 400 p. (In Russian).

Skripnik NV, Grib VA, Kubarich NІ, Vatseba TS. Pathogenetic basis of neurological disorders in patients with hypothyroidism and its correction (current review and personal data). Praktikuiuchii lіkar. 2012;4:55-60. (In Ukrainian).

Solov'ev AA, Marizin SA. Электронейромиографические параметры нервов верхних конечностей у больных хроническим гипотиреозом [Electroneuromyographic parameters of the nerves of the upper limbs in patients with chronic hypothyroidism]. In: Jendokrinologicheskoj sluzhbe Udmurtii 50 let [Endocrinology Service of Udmurtia is 50 years]. Izhevsk; 2005. (In Russian).

Strokov IA, Strokov KI, Dadaeva EE, Afonina ZhA. Actovegin in the treatment of diseases of the nervous system. Rossijskij Medicinskij Zhurnal. 2008;12:1665. (In Russian).

Strokov IA, Fokina AS, Golovacheva VA. Pregabalin in the treatment of painful diabetic polyneuropathy. Rossijskij medicinskij zhurnal. 2013;9:422. (In Russian).

Tovazhnianskaya EL. Neurological complications of primary hypothyroidism of various origin. Mezhdunarodnyj Medicinskij Zhurnal. 2013;1:15-9. (In Russian).

Shishkova VN. Prospects of Actovegin administration in patients with metabolic syndrome and prediabetes. Modern views on carbohydrate metabolism prevalence. Rossijskij Medicinskij Zhurnal. 2007;27:2066. (In Russian).

Beghi E, Delodovici ML, Bogliun G, Crespi V, Paleari F, Gamba P, Capra M, Zarrelli M. Hypothyroidism and polyneuropathy. J Neurol Neurosurg Psychiatry. 1989;52(12):1420-3. doi: 10.1136/jnnp.52.12.1420.

El-Salem K, Ammani F. Neurophysiological changes in neurologically asymptomatic hypothyroid patients: a prospective cohort study. J Clin Neurophysiol. 2006;23(6):568-72. doi: 10.1097/01.wnp.0000231273.22681.0e.

Watson JC, Dyck PJ. Peripheral neuropathy: a practical approach to diagnosis and symptom management. Mayo Clin Proc. 2015;90(7):940-51. doi: 10.1016/j.mayocp.2015.05.004.

Kececi H, Degirmenci Y. Hormone replacement therapy in hypothyroidism and nerve conduction study. Neurophysiol Clin. 2006;36(2):79-83. doi: 10.1016/j.neucli.2006.04.001.

Machicao F, Muresanu DF, Hundsberger H, Pflüger M, Guekht A. Pleiotropic neuroprotective and metabolic effects of Actovegin. Therapia. 2013;2(77):2-7. (In Russian).

Mahadule AA, Jadhao PS, Phatak MS. Motor conduction parameters in recently diagnosed and untreated hypothyroidism. Ann Neurosci. 2015;22(1):6-10. doi: 10.5214/ans.0972.7531.220103.

Penza P, Lombardi R, Camozzi F, Ciano C, Lauria G. Painful neuropathy in subclinical hypothyroidism: clinical and neuropathological recovery after hormone replacement therapy. Neurol Sci. 2009;30(2):149-51. doi: 10.1007/s10072-009-0026-x.




DOI: https://doi.org/10.22141/2224-0721.13.4.2017.106652

Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

 

© "Publishing House "Zaslavsky", 1997-2017

 

 Яндекс.МетрикаSeo анализ сайта Рейтинг@Mail.ru