Sleep disorders in diabetes mellitus type 1 depending on glycemia daily monitoring and achievement of glycemia target levels
Background. Sleep disorders occur in more than 50 % of the population of developed countries. Changes both in the structure and duration of sleep impact the somatic state of patients. The role of sleep is significant for the regulation of various body functions, hormone secretion, metabolic processes, and glucose homeostasis. The purpose of the study was to access sleep parameters and respiratory events of sleep depending on glycemia level during sleep for patients with type 1 diabetes mellitus. Materials and methods. The study involved 57 patients with type 1 diabetes. Depending on glycemia level during sleep all patients were divided into 3 groups: group 1 (n = 14) included the patients with sleeping glucose less than 3.9 mmol/l; group 2 (n = 25) included the patients with glycemic value 3.9–6.9 mmol/l; group 3 (n = 18) — 7.0–10.0 mmol/l. Glycated hemoglobin, daily monitoring of glycemia, polysomnography were determined in all patients. Results. The study found insufficient duration of total sleep time, a lack of slow sleep stages, more pronounced in patients with decompensation and nocturnal hypoglycemia regardless of diabetes compensation and sleeping hypoglycemia presence. Obstructive sleep apnea is more common in patients with sleeping hypoglycemia, the average duration of this apnea increases with a decrease in the mean value of glycemia on the day before bedtime. Conclusions. The revealed disturbances in sleep structure and the peculiarities of respiration in a sleep with type 1 diabetes can be one of the reasons for the decline in the quality of life of patients with type 1 diabetes.
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