The relationship between depressive disorders and the state of cognitive function in elderly patients with type 2 diabetes mellitus

N.N. Zherdоva

Abstract


Background. Depression is a risk factor of diabetes mellitus (DM) and negatively affects its course with an increased risk of complications. The aim of the study was to assess the state of cognitive function in elderly patients with type 2 DM (DM2) with and without depression. Materials and methods. 115 patients with DM2 were examined, including 78 women and 37 men. Patients were divided into 2 groups, with and without depressive disorders. Assessment of depressive symptoms was performed using self-questionnaire of depression (CES-D). Evaluation of cognitive manifestations was carried out in the morning with the following methods: “the 5 words” test, the Mini-Mental State Examination, Frontal Assessment Battery, clock drawing test. Results. In 68.7 % of elderly patients with DM2, we have not found depressive disorders according to CES-D, mild manifestations were observed in 17.4 % of patients, moderate — in 10.4 % and 3.5 % of patients had severe symptoms of depression. Persons with depressive disorders had a significant decline in cognitive function. In patients with DM with moderate to severe symptoms of depression, the state of cognitive function was significantly worse compared with patients, who have mild symptoms of depression or no depression. Conclusions. All patients with DM2 should be screened for the presence of depressive disorders in order to prevent violations of cognitive functions.


Keywords


diabetes mellitus; depressive disorders; cognitive impairment; depression; memory

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DOI: https://doi.org/10.22141/2224-0721.13.2.2017.100597

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